GYKI-52895
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| Identifiers | |
|---|---|
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| Synonyms | 4-(8,9-Dihydro-8-methyl-7H-1,3-dioxolo[4,5-h][2,3]benzodiazepin-5-yl)benzenamine |
| CAS Number | 869360-93-0 |
| PubChem (CID) | 3539 |
| ChemSpider |
3418  Y |
| KEGG |
C15094 Y |
| Chemical and physical data | |
| Formula | C17H17N3O2 |
| Molar mass | 295.34 g/mol |
| 3D model (Jmol) | Interactive image |
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| (verify) | |
GYKI-52895 is a drug which is a 2,3-benzodiazepine derivative. Unlike other similar drugs, GYKI-52895 is a selective dopamine reuptake inhibitor,[1][2] which presumably would produce stimulant effects in vivo.
See also
- GYKI-52,466, another 2,3-benzodiazepine with other than GABAergic function
- Tifluadom
- Lufuradom
- Benzodiazepine
- Substituted methylenedioxyphenethylamine
References
- ↑ Horváth K, Szabó H, Pátfalusi M, Berzsenyi P, Andrási F. Pharmacological Effects of GYKI 52895, a New Selective Dopamine Uptake Inhibitor. European Journal of Pharmacology. 1990; 183(4):1416-1417.
- ↑ Huang CL, Chen HC, Huang NK, Yang DM, Kao LS, Chen JC, Lai HL, Chern Y. Modulation of Dopamine Transporter Activity by Nicotinic Acetylcholine Receptors and Membrane Depolarization in Rat Pheochromocytoma PC12 Cells. Journal of Neurochemistry. 1999; 72(6): 2437–2444.
| 1,4-Benzodiazepines |
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|---|---|
| 1,5-Benzodiazepines | |
| 2,3-Benzodiazepines* | |
| Triazolobenzodiazepines | |
| Imidazobenzodiazepines | |
| Oxazolobenzodiazepines | |
| Thienodiazepines | |
| Thienotriazolodiazepines | |
| Thienobenzodiazepines* | |
| Pyridodiazepines | |
| Pyridotriazolodiazepines | |
| Pyrazolodiazepines | |
| Pyrrolodiazepines | |
| Tetrahydroisoquinobenzodiazepines | |
| Pyrrolobenzodiazepines* | |
| Benzodiazepine prodrugs | |
* atypical activity profile (not GABAA receptor ligands) | |
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