MKX
This article is about the protein. For the Mortal Kombat video game, see Mortal Kombat X. For other uses, see MKX (disambiguation).
| MKX | |||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||||||||||
| Aliases | MKX, C10orf48, IFRX, IRXL1, mohawk homeobox | ||||||||||||||||
| External IDs | MGI: 2687286 HomoloGene: 72239 GeneCards: MKX | ||||||||||||||||
| Genetically Related Diseases | |||||||||||||||||
| smallpox[1] | |||||||||||||||||
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| Orthologs | |||||||||||||||||
| Species | Human | Mouse | |||||||||||||||
| Entrez | |||||||||||||||||
| Ensembl | |||||||||||||||||
| UniProt | |||||||||||||||||
| RefSeq (mRNA) | |||||||||||||||||
| RefSeq (protein) | |||||||||||||||||
| Location (UCSC) | Chr 10: 27.67 – 27.75 Mb | Chr 18: 6.91 – 7 Mb | |||||||||||||||
| PubMed search | [2] | [3] | |||||||||||||||
| Wikidata | |||||||||||||||||
| View/Edit Human | View/Edit Mouse |
Homeobox protein Mohawk, also known as iroquois homeobox protein-like 1, is a protein that in humans is encoded by the MKX (mohawk homeobox) gene.[4]
Function
MKX is a member of an Iroquois (IRX) family-related class of 'three-amino acid loop extension' (TALE) atypical homeobox proteins characterized by 3 additional amino acids in the loop region between helix I and helix II of the homeodomain.[4][5]
References
- ↑ "Diseases that are genetically associated with MKX view/edit references on wikidata".
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- 1 2 "Entrez Gene: mohawk homeobox".
- ↑ Anderson DM, Arredondo J, Hahn K, Valente G, Martin JF, Wilson-Rawls J, Rawls A (March 2006). "Mohawk is a novel homeobox gene expressed in the developing mouse embryo". Dev. Dyn. 235 (3): 792–801. doi:10.1002/dvdy.20671. PMID 16408284.
Further reading
- Robertson NG, Khetarpal U, Gutiérrez-Espeleta GA, et al. (1994). "Isolation of novel and known genes from a human fetal cochlear cDNA library using subtractive hybridization and differential screening.". Genomics. 23 (1): 42–50. doi:10.1006/geno.1994.1457. PMID 7829101.
- Weinmann A, Galle PR, Teufel A (2005). "In silico characterization of an Iroquois family-related homeodomain protein.". Int. J. Mol. Med. 16 (3): 443–8. doi:10.3892/ijmm.16.3.443. PMID 16077953.
- Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928
. PMID 15489334. - Kimura K, Wakamatsu A, Suzuki Y, et al. (2006). "Diversification of transcriptional modulation: large-scale identification and characterization of putative alternative promoters of human genes.". Genome Res. 16 (1): 55–65. doi:10.1101/gr.4039406. PMC 1356129. PMID 16344560.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
- Anderson DM, Arredondo J, Hahn K, et al. (2006). "Mohawk is a novel homeobox gene expressed in the developing mouse embryo.". Dev. Dyn. 235 (3): 792–801. doi:10.1002/dvdy.20671. PMID 16408284.
- Barbe L, Lundberg E, Oksvold P, et al. (2008). "Toward a confocal subcellular atlas of the human proteome.". Mol. Cell Proteomics. 7 (3): 499–508. doi:10.1074/mcp.M700325-MCP200. PMID 18029348.
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
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