SLC5A6
| SLC5A6 | ||||||
|---|---|---|---|---|---|---|
| Identifiers | ||||||
| Aliases | SLC5A6, SMVT, solute carrier family 5 member 6 | |||||
| External IDs | MGI: 2660847 HomoloGene: 23277 GeneCards: SLC5A6 | |||||
| RNA expression pattern | ||||||
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| More reference expression data | ||||||
| Orthologs | ||||||
| Species | Human | Mouse | ||||
| Entrez | ||||||
| Ensembl | ||||||
| UniProt | ||||||
| RefSeq (mRNA) | ||||||
| RefSeq (protein) | ||||||
| Location (UCSC) | Chr 2: 27.2 – 27.21 Mb | Chr 5: 31.04 – 31.05 Mb | ||||
| PubMed search | [1] | [2] | ||||
| Wikidata | ||||||
| View/Edit Human | View/Edit Mouse |
Sodium-dependent multivitamin transporter is a protein that in humans is encoded by the SLC5A6 gene.[3][4][5]
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ Prasad PD, Wang H, Kekuda R, Fujita T, Fei YJ, Devoe LD, Leibach FH, Ganapathy V (Apr 1998). "Cloning and functional expression of a cDNA encoding a mammalian sodium-dependent vitamin transporter mediating the uptake of pantothenate, biotin, and lipoate". J Biol Chem. 273 (13): 7501–6. doi:10.1074/jbc.273.13.7501. PMID 9516450.
- ↑ Wang H, Huang W, Fei YJ, Xia H, Yang-Feng TL, Leibach FH, Devoe LD, Ganapathy V, Prasad PD (Jul 1999). "Human placental Na+-dependent multivitamin transporter. Cloning, functional expression, gene structure, and chromosomal localization". J Biol Chem. 274 (21): 14875–83. doi:10.1074/jbc.274.21.14875. PMID 10329687.
- ↑ "Entrez Gene: SLC5A6 solute carrier family 5 (sodium-dependent vitamin transporter), member 6".
Further reading
- Prasad PD, Wang H, Huang W, et al. (1999). "Molecular and functional characterization of the intestinal Na+-dependent multivitamin transporter.". Arch. Biochem. Biophys. 366 (1): 95–106. doi:10.1006/abbi.1999.1213. PMID 10334869.
- Zempleni J, Steven Stanley J, Mock DM (2001). "Proliferation of peripheral blood mononuclear cells causes increased expression of the sodium-dependent multivitamin transporter gene and increased uptake of pantothenic acidopen star". The Journal of nutritional biochemistry. 12 (8): 465–473. doi:10.1016/S0955-2863(01)00162-0. PMID 11834205.
- Dey S, Subramanian VS, Chatterjee NS, et al. (2002). "Characterization of the 5' regulatory region of the human sodium-dependent multivitamin transporter, hSMVT.". Biochim. Biophys. Acta. 1574 (2): 187–92. doi:10.1016/s0167-4781(02)00226-9. PMID 11955628.
- Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241
. PMID 12477932. - Balamurugan K, Ortiz A, Said HM (2003). "Biotin uptake by human intestinal and liver epithelial cells: role of the SMVT system". Am. J. Physiol. Gastrointest. Liver Physiol. 285 (1): G73–7. doi:10.1152/ajpgi.00059.2003. PMID 12646417.
- Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
- Balamurugan K, Vaziri ND, Said HM (2005). "Biotin uptake by human proximal tubular epithelial cells: cellular and molecular aspects". Am. J. Physiol. Renal Physiol. 288 (4): F823–31. doi:10.1152/ajprenal.00375.2004. PMID 15561972.
- Otsuki T, Ota T, Nishikawa T, et al. (2007). "Signal sequence and keyword trap in silico for selection of full-length human cDNAs encoding secretion or membrane proteins from oligo-capped cDNA libraries". DNA Res. 12 (2): 117–26. doi:10.1093/dnares/12.2.117. PMID 16303743.
- Luo S, Kansara VS, Zhu X, et al. (2006). "Functional Characterization of Sodium-dependent Multivitamin Transporter (SMVT) in MDCK-MDR1 cells and its Utilization as a Target for Drug Delivery". Mol. Pharm. 3 (3): 329–39. doi:10.1021/mp0500768. PMC 2553563. PMID 16749865.
- Reidling JC, Nabokina SM, Said HM (2007). "Molecular mechanisms involved in the adaptive regulation of human intestinal biotin uptake: A study of the hSMVT system". Am. J. Physiol. Gastrointest. Liver Physiol. 292 (1): G275–81. doi:10.1152/ajpgi.00327.2006. PMID 16959947.
- Reidling JC, Said HM (2007). "Regulation of the human biotin transporter hSMVT promoter by KLF-4 and AP-2: confirmation of promoter activity in vivo". Am. J. Physiol., Cell Physiol. 292 (4): C1305–12. doi:10.1152/ajpcell.00360.2006. PMID 17135299.
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