Pheophorbidase

Pheophorbidase
Identifiers
EC number 3.1.1.82
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Pheophorbidase (EC 3.1.1.82, phedase, PPD) is an enzyme with systematic name pheophorbide-a hydrolase.[1][2][3] This enzyme catalyses the following chemical reaction

pheophorbide a + H2O pyropheophorbide a + methanol + CO2 (overall reaction)
(1a) pheophorbide a + H2O C-132-carboxypyropheophorbide a + methanol
(1b) C-132-carboxypyropheophorbide a pyropheophorbide a + CO2 (spontaneous)

This enzyme participates in the chlorophyll degradation in higher plants and algae.

References

  1. Suzuki, Y.; Doi, M.; Shioi, Y. (2002). "Two enzymatic reaction pathways in the formation of pyropheophorbide a". Photosynth. Res. 74: 225–233. doi:10.1023/A:1020919929608. PMID 16228561.
  2. Suzuki, Y.; Amano, T.; Shioi, Y. (2006). "Characterization and cloning of the chlorophyll-degrading enzyme pheophorbidase from cotyledons of radish". Plant Physiol. 140: 716–725. doi:10.1104/pp.105.071290. PMID 16384908.
  3. Hörtensteiner, S. (2006). "Chlorophyll degradation during senescence". Annu. Rev. Plant Biol. 57: 55–77. doi:10.1146/annurev.arplant.57.032905.105212. PMID 16669755.
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