ELTD1

ADGRL4
Identifiers
Aliases ADGRL4, ETL, KPG_003, ELTD1, adhesion G protein-coupled receptor L4
External IDs MGI: 2655562 HomoloGene: 11170 GeneCards: ADGRL4
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

64123

170757

Ensembl

ENSG00000162618

ENSMUSG00000039167

UniProt

Q9HBW9

Q923X1

RefSeq (mRNA)

NM_022159

NM_133222

RefSeq (protein)

NP_071442.2

NP_573485.2

Location (UCSC) Chr 1: 78.89 – 79.01 Mb Chr 3: 151.44 – 151.55 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

EGF, latrophilin and seven transmembrane domain-containing protein 1 is a latrophilin-like orphan receptor of the adhesion G protein-coupled receptor family. In humans this protein is encoded by the ELTD1 gene.[3][4] ELTD1 appears to have a role in angiogenesis, both physiological and pathological, as well as glioblastoma.[5]

See also

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Nechiporuk T, Urness LD, Keating MT (May 2001). "ETL, a novel seven-transmembrane receptor that is developmentally regulated in the heart. ETL is a member of the secretin family and belongs to the epidermal growth factor-seven-transmembrane subfamily". J Biol Chem. 276 (6): 4150–4157. doi:10.1074/jbc.M004814200. PMID 11050079.
  4. "Entrez Gene: ELTD1 EGF, latrophilin and seven transmembrane domain containing 1".
  5. Dricu, Anica; Serban, Florentina; Artene, Stefan-Alexandru; Georgescu, Ada Maria; Purcaru, Stefana Oana; Tache, Daniela Elise; Alexandru, Oana (December 2015). "Epidermal growth factor, latrophilin, and seven transmembrane domain-containing protein 1 marker, a novel angiogenesis marker". OncoTargets and Therapy: 3767. doi:10.2147/OTT.S93843.

Further reading


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