WNT8A

Identifiers

WNT8A, WNT8D, Wnt family member 8A

External IDs

MGI: 107924 HomoloGene: 7553 GeneCards: WNT8A

Gene ontology
Molecular function	• receptor agonist activity • receptor binding • frizzled binding
Cellular component	• extracellular fluid • proteinaceous extracellular matrix • extracellular region
Biological process	• canonical Wnt signaling pathway involved in neural crest cell differentiation • canonical Wnt signaling pathway • regulation of transcription involved in anterior/posterior axis specification • palate development • multicellular organism development • response to retinoic acid • neural crest cell fate commitment • neuron differentiation • canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment • beta-catenin destruction complex disassembly • Wnt signaling pathway
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse

Entrez


7478


20890

Ensembl


ENSG00000061492


ENSMUSG00000012282

UniProt


Q9H1J5


Q64527

RefSeq (mRNA)


NM_001300938 NM_001300939 NM_031933 NM_058244


NM_009290

RefSeq (protein)


NP_001287867.1 NP_001287868.1 NP_490645.1


NP_033316.1

Location (UCSC)

Chr 5: 138.08 – 138.09 Mb

Chr 18: 34.54 – 34.55 Mb

PubMed search

^[1]

^[2]

Wikidata

View/Edit Human

View/Edit Mouse

Protein Wnt-8a is a protein that in humans is encoded by the WNT8A gene.^[3] Wnt8a may be involved in development of early embryos as well as germ cell tumors.^[3]

References

Signaling pathway: Wnt signaling pathway

Ligand	WNT1 WNT2 WNT2B WNT3 WNT3A WNT4 WNT5A WNT5B WNT6 WNT7A WNT7B WNT8A WNT8B WNT9A WNT9B WNT10A WNT10B WNT11 WNT16

Receptor	Frizzled LRP5 LRP6

Second messenger	Dishevelled GSK-3 APC Beta-catenin

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