Methyclothiazide

Methyclothiazide
Clinical data

AHFS/Drugs.com	Consumer Drug Information
MedlinePlus	a682569
ATC code	C03AA08 (WHO)
Identifiers
IUPAC name 6-Chloro-3-(chloromethyl)-2-methyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide
CAS Number	135-07-9^Y
PubChem (CID)	4121
IUPHAR/BPS	7235
DrugBank	DB00232^N
ChemSpider	3978^N
UNII	L3H46UAC61^N
KEGG	D00656^N
ChEMBL	CHEMBL1577^N
ECHA InfoCard	100.004.703
Chemical and physical data
Formula	C₉H₁₁Cl₂N₃O₄S₂
Molar mass	360.24 g/mol
^NY (what is this?) (verify)

Methyclothiazide is a thiazide diuretic.

References

Symporter inhibitors

Na⁺-Cl⁻	Thiazides: Bendroflumethiazide Chlorothiazide Cyclopenthiazide Cyclothiazide Hydrochlorothiazide Hydroflumethiazide Methyclothiazide Polythiazide Trichlormethiazide; Others: Chlortalidone (chlorthalidone) Metolazone

Na⁺-K⁺-Cl⁻	Bumetanide Furosemide

Antihypertensives: diuretics (C03)

Sulfonamides
(and etacrynic acid)

CA inhibitors (at PT)	Acetazolamide

Loop (Na-K-Cl at AL)	Furosemide^# Bumetanide Etacrynic acid Etozolin Muzolimine Ozolinone Piretanide Tienilic acid Torasemide

Thiazides (Na-Cl at DCT, Calcium-sparing)	Altizide Bendroflumethiazide Chlorothiazide Cyclopenthiazide Cyclothiazide Epitizide Hydrochlorothiazide^# Hydroflumethiazide Mebutizide Methyclothiazide Polythiazide Trichlormethiazide

Thiazide-likes (primarily DCT)	Quinethazone Clopamide Chlortalidone Mefruside Clofenamide Metolazone Meticrane Xipamide Indapamide Clorexolone Fenquizone

Potassium-sparing (at CD)

ESC blockers	Amiloride^# Triamterene Benzamil

Aldosterone antagonists	Spirolactones: Spironolactone^# Eplerenone Potassium canrenoate Canrenone Non-steroidal: Finerenone

Osmotic diuretics (PT, DL)

Vasopressin receptor inhibitors
(DCT and CD)

Other

Ethanol, Isopropanol, 2M2B
mercurial diuretics (Chlormerodrin, Mersalyl, Meralluride)
Theobromine
Cicletanine

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

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