Mesotrione

Mesotrione
Names
IUPAC name
2-[4-(Methylsulfonyl)-2-nitrobenzoyl]cyclohexane-1,3-dione
Identifiers
104206-82-8 YesY
3D model (Jmol) Interactive image
ChEBI CHEBI:38321 YesY
ChemSpider 153301 YesY
ECHA InfoCard 100.111.661
PubChem 175967
UNII 48TR68G21T YesY
Properties
C14H13NO7S
Molar mass 339.32 g·mol−1
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
YesY verify (what is YesYN ?)
Infobox references

Mesotrione is an herbicide sold under the brand names Callisto and Tenacity that was brought to market by Syngenta in 2001.[1] It is a synthetic analog of leptospermone developed to mimic the effects of this natural herbicide.[2] Mesotrione is a member of the class of HPPD inhibitors, which all work by inhibiting the plant enzyme 4-hydroxyphenylpyruvate dioxygenase.[3] In plants, HPPD is necessary for carotenoid biosynthesis; carotenoids in turn protect chlorophyll from being degraded by sunlight.[4] When an HPPD inhibitor is sprayed on a plant, it prevents carotenoid from being made, chlorophyll degrades and the plant dies.

Sales by Syngenta were more than $400 million per year in 2011 but worldwide patent rights started to expire in 2012, opening the market to generic competition.[1]

See also

References

  1. 1 2 Dr. Nigel Uttley for Farm Chemicals International. June 3, 2011 Product Profile: Mesotrione
  2. ↑ Derek Cornes (2005). "Callisto: a very successful maize herbicide inspired by allelochemistry". Fourth World Congress on Alleopathy. The Regional Institute Ltd. Retrieved May 26, 2011.
  3. ↑ Moran, GR (Jan 2005). "4-Hydroxyphenylpyruvate dioxygenase" (PDF). Arch Biochem Biophys. 433 (1): 117–28. doi:10.1016/j.abb.2004.08.015. PMID 15581571.
  4. ↑ "Tenacity Herbicide". Syngenta.
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