TIMM23

TIMM23B

Identifiers

TIMM23B, TIMM23, bA592B15.7, translocase of inner mitochondrial membrane 23 homolog B

External IDs

HomoloGene: 140621 GeneCards: TIMM23B

Gene ontology
Molecular function	• molecular function • P-P-bond-hydrolysis-driven protein transmembrane transporter activity • protein channel activity
Cellular component	• membrane • cellular component • integral component of mitochondrial inner membrane • mitochondrial inner membrane presequence translocase complex • integral component of membrane • mitochondrion • mitochondrial inner membrane
Biological process	• protein import into mitochondrial matrix • biological process • intracellular protein transport • protein transport • transport
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


100652748


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ENSG00000204152


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Q5SRD1


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RefSeq (mRNA)


NM_001290117 NM_001290118


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RefSeq (protein)


n/a


n/a

Location (UCSC)

Chr 10: 49.94 – 49.97 Mb

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PubMed search

^[1]

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View/Edit Human

Mitochondrial import inner membrane translocase subunit Tim23 is an enzyme that in humans is encoded by the TIMM23 gene.^[2]^[3]

See also

References

↑ "Human PubMed Reference:".
↑ Bauer MF, Gempel K, Reichert AS, Rappold GA, Lichtner P, Gerbitz KD, Neupert W, Brunner M, Hofmann S (Jul 1999). "Genetic and structural characterization of the human mitochondrial inner membrane translocase". J Mol Biol. 289 (1): 69–82. doi:10.1006/jmbi.1999.2751. PMID 10339406.
↑ "Entrez Gene: TIMM23 translocase of inner mitochondrial membrane 23 homolog (yeast)".

Further reading

Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Guo Y, Cheong N, Zhang Z, et al. (2004). "Tim50, a component of the mitochondrial translocator, regulates mitochondrial integrity and cell death". J. Biol. Chem. 279 (23): 24813–25. doi:10.1074/jbc.M402049200. PMID 15044455.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Yamamoto H, Esaki M, Kanamori T, et al. (2002). "Tim50 is a subunit of the TIM23 complex that links protein translocation across the outer and inner mitochondrial membranes". Cell. 111 (4): 519–28. doi:10.1016/S0092-8674(02)01053-X. PMID 12437925.
Moro F, Sirrenberg C, Schneider HC, et al. (1999). "The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix". EMBO J. 18 (13): 3667–75. doi:10.1093/emboj/18.13.3667. PMC 1171444. PMID 10393182.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, et al. (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.

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