Neurophilic

In neuroscience, a neurophilic substance is one that has an affinity for nervous tissue, often involving a type of tangential cell migration. Neurophilic migration is (heterotypic) cellular migration in which the cells migrate in close apposition to axonal fascicles as opposed to chain migration (homotypic) when the cells migrate in close contact to each other without using a glial or neuronal scaffold.[1][2][3]

References

  1. Ono, K. and Kawamura, K. (1990). Mode of neuronal migration of the pontine stream in fetal mice. Anat. Embryol. 182, 11-19
  2. Rakic, P. (1990). Principles of neural cell migration. Experientia 46, 882-891
  3. Yee, K. T., Simon, H. H., Tessier-Lavigne, M. and O’Leary, D. M. (1999). Extension of long leading processes and neuronal migration in the mammalian brain directed by the chemoattractant netrin-1. Neuron 24, 607-622


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