NMN nucleosidase

NMN nucleosidase
Identifiers
EC number 3.2.2.14
CAS number 37237-49-3
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a NMN nucleosidase (EC 3.2.2.14) is an enzyme that catalyzes the chemical reaction

nicotinamide D-ribonucleotide + H2O D-ribose 5-phosphate + nicotinamide

Thus, the two substrates of this enzyme are nicotinamide D-ribonucleotide and H2O, whereas its two products are D-ribose 5-phosphate and nicotinamide.

This enzyme belongs to the family of hydrolases, specifically those glycosylases that hydrolyse N-glycosyl compounds. The systematic name of this enzyme class is nicotinamide-nucleotide phosphoribohydrolase. Other names in common use include NMNase, nicotinamide mononucleotide nucleosidase, nicotinamide mononucleotidase, NMN glycohydrolase, and NMNGhase. This enzyme participates in nicotinate and nicotinamide metabolism.

References


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