NAGA (gene)

NAGA
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases NAGA, D22S674, GALB, alpha-N-acetylgalactosaminidase
External IDs MGI: 1261422 HomoloGene: 221 GeneCards: NAGA
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

4668

17939

Ensembl

ENSG00000198951

ENSMUSG00000022453

UniProt

P17050

Q9QWR8

RefSeq (mRNA)

NM_000262

NM_008669

RefSeq (protein)

NP_000253.1
NP_000253.1

NP_032695.3

Location (UCSC) Chr 22: 42.06 – 42.07 Mb Chr 15: 82.33 – 82.34 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Alpha-N-acetylgalactosaminidase is an enzyme that in humans is encoded by the NAGA gene.[3]

NAGA encodes the lysosomal enzyme alpha-N-acetylgalactosaminidase, which cleaves alpha-N-acetylgalactosaminyl moieties from glycoconjugates. Mutations in NAGA have been identified as the cause of Schindler disease types I and II (type II also known as Kanzaki disease).[3]

References

Further reading


This article is issued from Wikipedia - version of the 6/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.