Mannosylglycerate hydrolase

Mannosylglycerate hydrolase
Identifiers
EC number 3.2.1.170
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Mannosylglycerate hydrolase (EC 3.2.1.170, 2-O-(6-phospho-mannosyl)-D-glycerate hydrolase, alpha-mannosidase, mngB (gene)) is an enzyme with systematic name 2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate acylhydrolase.[1] This enzyme catalyses the following chemical reaction

2-O-(6-phospho-alpha-D-mannosyl)-D-glycerate + H2O D-mannose 6-phosphate + D-glycerate

The enzyme participates in the mannosylglycerate degradation pathway of some bacteria.

References

  1. Sampaio, M.M.; Chevance, F.; Dippel, R.; Eppler, T.; Schlegel, A.; Boos, W.; Lu, Y.J.; Rock, C.O. (2004). "Phosphotransferase-mediated transport of the osmolyte 2-O-α-mannosyl-D-glycerate in Escherichia coli occurs by the product of the mngA (hrsA) gene and is regulated by the mngR (farR) gene product acting as repressor". J. Biol. Chem. 279: 5537–5548. doi:10.1074/jbc.m310980200. PMID 14645248.
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