Keratan-sulfate endo-1,4-beta-galactosidase

Keratan-sulfate endo-1,4-beta-galactosidase
Identifiers
EC number 3.2.1.103
CAS number 55072-01-0
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

Keratan-sulfate endo-1,4-beta-galactosidase (EC 3.2.1.103, endo-beta-galactosidase, keratan sulfate endogalactosidase, keratanase, keratan-sulfate 1,4-beta-D-galactanohydrolase) is an enzyme with systematic name keratan-sulfate 4-beta-D-galactanohydrolase.[1] This enzyme catalyses the following chemical reaction

Endohydrolysis of (1->4)-beta-D-galactosidic linkages in keratan sulfate

Hydrolyses the 1,4-beta-D-galactosyl linkages adjacent to 1,3-N-acetyl-alpha-D-glucosaminyl residues.

References

  1. Fukuda, M.N.; Matsumara, G. (1976). "Endo-β-galactosidase of Escherichia freundii. Purification and endoglycosidic action on keratan sulfates, oligosaccharides, and blood group active glycoprotein". J. Biol. Chem. 251: 6218–6225. PMID 135762.
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