Familial hypertriglyceridemia

Familial hypertriglyceridemia is an autosomal dominant condition occurring in approximately 1% of the population.^[1] Triglyceride levels, but not cholesterol, are elevated as a result of excess hepatic production of VLDL or heterozygous LPL deficiency. The condition is associated with premature coronary disease, though treatment sometimes differs from hypercholesterolemia. Affected individuals are at risk for chylomicronemia syndrome, characterized by elevated chylomicrons in the blood. They are also at risk of pancreatitis, especially when triglyceride levels exceed 1000mg/dL.

References

↑ Boman H,Hazzard WR, AlbersJJ, et ah Frequency of monogenic forms of hyperlipidemia in a normal population. AmJ ttum Genet 27:19A,1975.

Inborn error of lipid metabolism: dyslipidemia (E78, 272.0–272.6)

Hyperlipidemia

Hypolipoproteinemia

Hypoalphalipoproteinemia/HDL	Lecithin cholesterol acyltransferase deficiency Tangier disease

Hypobetalipoproteinemia/LDL	Abetalipoproteinemia Apolipoprotein B deficiency Chylomicron retention disease

Lipodystrophy

Barraquer–Simons syndrome

Other

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Familial hypertriglyceridemia

See also

References