Ent-kaurenoic acid oxidase
| Ent-kaurenoic acid oxidase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.14.13.79 | ||||||||
| CAS number | 337507-95-6 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
Ent-kaurenoic acid oxidase (EC 1.14.13.79) is an enzyme with systematic name ent-kaur-16-en-19-oate,NADPH:oxygen oxidoreductase (hydroxylating).[1] This enzyme catalyses the following chemical reaction
- ent-kaur-16-en-19-oate + 3 NADPH + 3 H+ + 3 O2 gibberellin A12 + 3 NADP+ + 4 H2O (overall reaction)
- (1a) ent-kaur-16-en-19-oate + NADPH + H+ + O2 ent-7alpha-hydroxykaur-16-en-19-oate + NADP+ + H2O
- (1b) ent-7alpha-hydroxykaur-16-en-19-oate + NADPH + H+ + O2 gibberellin A12 aldehyde + NADP+ + 2 H2O
- (1c) gibberellin A12 aldehyde + NADPH + H+ + O2 gibberellin A12 + NADP+ + H2O
Ent-kaurenoic acid oxidase requires cytochrome P450.
References
- ↑ Helliwell, C.A.; Chandler, P.M.; Poole, A.; Dennis, E.S.; Peacock, W.J. (2001). "The CYP88A cytochrome P450, ent-kaurenoic acid oxidase, catalyzes three steps of the gibberellin biosynthesis pathway". Proc. Natl. Acad. Sci. USA. 98 (4): 2065–2070. doi:10.1073/pnas.041588998. PMC 29382
. PMID 11172076.
External links
- Ent-kaurenoic acid oxidase at the US National Library of Medicine Medical Subject Headings (MeSH)
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