Bromochlorosalicylanilide

Bromochlorosalicylanilide
Clinical data

ATC code	D01AE01 (WHO)
Identifiers
IUPAC name 5-Bromo-N-(4-chlorophenyl)-2-hydroxybenzamide
Synonyms	Bromosalicylchloranilide Multifungin Salifungin
CAS Number	3679-64-9
PubChem (CID)	77254
ChemSpider	69679
UNII	6GK715PWMQ^Y
ChEMBL	CHEMBL153192
ECHA InfoCard	100.020.870
Chemical and physical data
Formula	C₁₃H₉BrClNO₂
Molar mass	326.57 g/mol
3D model (Jmol)	Interactive image
SMILES Brc2cc(C(=O)Nc1ccc(Cl)cc1)c(O)cc2

Bromochlorosalicylanilide is an antifungal.^[1] It may cause allergic contact dermatitis in some individuals.^[2]

References

↑ Weuffen, Wolfgang; Wagner, Guenther; Singer, Dietmar; Petermann, M. (1966). "2-Hydroxythiobenzamides and 2-hydroxythiobenzanilides. III. Fungicidal properties". Pharmazie. 21 (10): 613–19.
↑ Buckley D B (1986). "Allergic contact dermatitis to bromsalicylchloranilide". Contact dermatitis. 14 (5): 319. doi:10.1111/j.1600-0536.1986.tb05290.x. PMID 3743047.

Wall/
membrane

Ergosterol
inhibitors

Imidazoles	Topical: bifonazole^‡ butoconazole chlormidazole^‡ clotrimazole^# croconazole^‡ econazole fenticonazole^‡ flutrimazole isoconazole^‡ ketoconazole luliconazole miconazole^# neticonazole^‡ omoconazole^‡ oxiconazole sertaconazole sulconazole tioconazole Systemic: ketoconazole

Triazoles	Topical: efinaconazole fluconazole^# fosfluconazole terconazole Systemic: fluconazole^# hexaconazole^‡ isavuconazole itraconazole posaconazole voriconazole Unknown: albaconazole^‡ ravuconazole^†

Thiazoles	Topical: abafungin^‡

Allylamines	Topical: naftifine terbinafine Systemic: terbinafine

Benzylamines	Topical: butenafine

Others

Intracellular

Pyrimidine analogues/ thymidylate synthase inhibitors	flucytosine^#

Mitotic inhibitors	griseofulvin^#

Aminoacyl tRNA synthetase inhibitors	tavaborole

Others

This article is issued from Wikipedia - version of the 10/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.