2-methylisoborneol synthase
| 2-methylisoborneol synthase | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 4.2.3.118 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
2-methylisoborneol synthase (EC 4.2.3.118, sco7700, 2-MIB cyclase, MIB synthase, MIBS) is an enzyme with systematic name (E)-2-methylgeranyl-diphosphate diphosphate-lyase (cyclizing, 2-methylisoborneol-forming).[1][2][3] This enzyme catalyses the following chemical reaction
- (E)-2-methylgeranyl diphosphate + H2O 2-methylisoborneol + diphosphate
The product, 2-methylisoborneol, is a characteristic odiferous compound with a musty smell produced by soil microorganisms.
References
- ↑ Wang, C.M.; Cane, D.E. (2008). "Biochemistry and molecular genetics of the biosynthesis of the earthy odorant methylisoborneol in Streptomyces coelicolor". J. Am. Chem. Soc. 130: 8908–8909. doi:10.1021/ja803639g. PMID 18563898.
- ↑ Komatsu, M.; Tsuda, M.; Omura, S.; Oikawa, H.; Ikeda, H. (2008). "Identification and functional analysis of genes controlling biosynthesis of 2-methylisoborneol". Proc. Natl. Acad. Sci. USA. 105: 7422–7427. doi:10.1073/pnas.0802312105. PMID 18492804.
- ↑ Giglio, S.; Chou, W.K.; Ikeda, H.; Cane, D.E.; Monis, P.T. (2011). "Biosynthesis of 2-methylisoborneol in cyanobacteria". Environ. Sci. Technol. 45: 992–998. doi:10.1021/es102992p. PMID 21174459.
External links
- 2-methylisoborneol synthase at the US National Library of Medicine Medical Subject Headings (MeSH)
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