2'-Hydroxyisoflavone reductase

2'-hydroxyisoflavone reductase
Identifiers
EC number 1.3.1.45
CAS number 128449-69-4
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum
Gene Ontology AmiGO / EGO

In enzymology, a 2'-hydroxyisoflavone reductase (EC 1.3.1.45) is an enzyme that catalyzes the chemical reaction

vestitone + NADP+ 2'-hydroxyformononetin + NADPH + H+

Thus, the two substrates of this enzyme are vestitone and NADP+, whereas its 3 products are 2'-hydroxyformononetin, NADPH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-CH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is vestitone:NADP+ oxidoreductase. Other names in common use include NADPH:2'-hydroxyisoflavone oxidoreductase, isoflavone reductase, and 2',7-dihydroxy-4',5'-methylenedioxyisoflavone reductase.

References


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