(S)-beta-macrocarpene synthase

(S)-beta-macrocarpene synthase
Identifiers
EC number 5.5.1.17
Databases
IntEnz IntEnz view
BRENDA BRENDA entry
ExPASy NiceZyme view
KEGG KEGG entry
MetaCyc metabolic pathway
PRIAM profile
PDB structures RCSB PDB PDBe PDBsum

(S)-beta-macrocarpene synthase (EC 5.5.1.17, TPS6, TPS11) is an enzyme with systematic name (S)-beta-macrocarpene lyase (decyclizing).[1] This enzyme catalyses the following chemical reaction

(S)-beta-bisabolene (S)-beta-macrocarpene

The synthesis of (S)-beta-macrocarpene from (2E,6E)-farnesyl diphosphate proceeds in two steps.

References

  1. Kollner, T.G.; Schnee, C.; Li, S.; Svatos, A.; Schneider, B.; Gershenzon, J.; Degenhardt, J. (2008). "Protonation of a neutral (S)-β-bisabolene intermediate is involved in (S)-β-macrocarpene formation by the maize sesquiterpene synthases TPS6 and TPS11". J. Biol. Chem. 283: 20779–20788. doi:10.1074/jbc.m802682200. PMID 18524777.

External links

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