Isopiperitenol dehydrogenase

In enzymology, an isopiperitenol dehydrogenase (EC 1.1.1.223) is an enzyme that catalyzes the chemical reaction

(-)-trans-isopiperitenol + NAD+ (-)-isopiperitenone + NADH + H+
isopiperitenol dehydrogenase
Identifiers
EC number1.1.1.223
CAS number96595-05-0
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

Thus, the two substrates of this enzyme are (-)-trans-isopiperitenol and NAD+, whereas its 3 products are (-)-isopiperitenone, NADH, and H+.

This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is (-)-trans-isopiperitenol:NAD+ oxidoreductase. This enzyme participates in monoterpenoid biosynthesis.

References

    • Kjonaas RB, Venkatachalam KV, Croteau R (1985). "Metabolism of monoterpenes: oxidation of isopiperitenol to isopiperitenone, and subsequent isomerization to piperitenone by soluble enzyme preparations from peppermint (Mentha piperita) leaves". Arch. Biochem. Biophys. 238 (1): 49–60. doi:10.1016/0003-9861(85)90139-0. PMID 3885858.


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