Etoxeridine

Etoxeridine (Carbetidine, Atenos) is a 4-phenylpiperidine derivative that is related to the clinically used opioid analgesic drug pethidine (meperidine).

Etoxeridine
Clinical data
Other namesEtoxeridine, Carbetidine, Atenos
ATC code
  • none
Legal status
Legal status
Identifiers
CAS Number
PubChem CID
DrugBank
ChemSpider
UNII
ChEMBL
CompTox Dashboard (EPA)
ECHA InfoCard100.006.750
Chemical and physical data
FormulaC18H27NO4
Molar mass321.417 g·mol−1
3D model (JSmol)
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Etoxeridine was developed in the 1950s[1] and investigated for use in surgical anesthesia, however it was never commercialized and is not currently used in medicine.[2][3][4] As with other opioids which were not in clinical use during the drafting of the Controlled Substances Act, it is categorized as a Schedule I narcotic.

References

  1. BE 558883
  2. Merlevede E, Levis S (1958). "Pharmacological study of carbetidine, a new synthetic analgesic". Archives Internationales de Pharmacodynamie et de Thérapie (in French). 115 (1–2): 213–232. PMID 13545901.
  3. Sironi PG (1959). "Brief note on a new synthetic analgesic: carbetidine hydrochloride". Minerva Anestesiologica (in Italian). 25 (6): 251–254. PMID 13674097.
  4. Crawford JS, Foldes FF (August 1959). "Studies on the respiratory and circulatory effects of carbetidine HCI used for supplementation of thiopentone sodium-nitrous oxide-oxygen anaesthesia". British Journal of Anaesthesia. 31 (8): 348–51. doi:10.1093/bja/31.8.348. PMID 13812715.
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