D-arabinitol dehydrogenase (NADP+)
D-arabinitol dehydrogenase (NADP+) (EC 1.1.1.287, NADP+-dependent D-arabitol dehydrogenase, ARD1p, D-arabitol dehydrogenase 1) is an enzyme with systematic name D-arabinitol:NADP+ oxidoreductase.[1] This enzyme catalyses the following chemical reaction
- (1) D-arabinitol + NADP+ D-xylulose + NADPH + H+
- (2) D-arabinitol + NADP+ D-ribulose + NADPH + H+
| D-arabinitol dehydrogenase (NADP+) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.1.1.287 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The enzyme present in the fungus Uromyces fabae can make use D-arabinitol and D-mannitol in the forward direction, and D-xylulose, D-ribulose and D-fructose in the reverse direction.
References
- Link T, Lohaus G, Heiser I, Mendgen K, Hahn M, Voegele RT (July 2005). "Characterization of a novel NADP(+)-dependent D-arabitol dehydrogenase from the plant pathogen Uromyces fabae". The Biochemical Journal. 389 (Pt 2): 289–95. doi:10.1042/BJ20050301. PMC 1175105. PMID 15796718.
External links
- D-arabinitol+dehydrogenase+(NADP+) at the US National Library of Medicine Medical Subject Headings (MeSH)
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