Acrylyl-CoA reductase (NADH)
Acrylyl-CoA reductase (NADH) (EC 1.3.1.95) is an enzyme with systematic name propanoyl-CoA:NAD+ oxidoreductase.[1][2] This enzyme catalyses the following chemical reaction
- propanoyl-CoA + NAD+ acryloyl-CoA + NADH + H+
| Acrylyl-CoA reductase (NADH) | |||||||||
|---|---|---|---|---|---|---|---|---|---|
| Identifiers | |||||||||
| EC number | 1.3.1.95 | ||||||||
| Databases | |||||||||
| IntEnz | IntEnz view | ||||||||
| BRENDA | BRENDA entry | ||||||||
| ExPASy | NiceZyme view | ||||||||
| KEGG | KEGG entry | ||||||||
| MetaCyc | metabolic pathway | ||||||||
| PRIAM | profile | ||||||||
| PDB structures | RCSB PDB PDBe PDBsum | ||||||||
| |||||||||
The reaction is catalysed in the opposite direction.
References
- Hetzel M, Brock M, Selmer T, Pierik AJ, Golding BT, Buckel W (March 2003). "Acryloyl-CoA reductase from Clostridium propionicum. An enzyme complex of propionyl-CoA dehydrogenase and electron-transferring flavoprotein". European Journal of Biochemistry. 270 (5): 902–10. doi:10.1046/j.1432-1033.2003.03450.x. PMID 12603323.
- Kandasamy V, Vaidyanathan H, Djurdjevic I, Jayamani E, Ramachandran KB, Buckel W, Jayaraman G, Ramalingam S (February 2013). "Engineering Escherichia coli with acrylate pathway genes for propionic acid synthesis and its impact on mixed-acid fermentation". Applied Microbiology and Biotechnology. 97 (3): 1191–200. doi:10.1007/s00253-012-4274-y. PMID 22810300.
External links
- Acrylyl-CoA+reductase+(NADH) at the US National Library of Medicine Medical Subject Headings (MeSH)
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