3-aci-nitropropanoate oxidase

In enzymology, a 3-aci-nitropropanoate oxidase (EC 1.7.3.5) is an enzyme that catalyzes the chemical reaction

3-aci-nitropropanoate + O2 + H2O 3-oxopropanoate + nitrite + H2O2
3-aci-nitropropanoate oxidase
Identifiers
EC number1.7.3.5
CAS number111940-52-4
Databases
IntEnzIntEnz view
BRENDABRENDA entry
ExPASyNiceZyme view
KEGGKEGG entry
MetaCycmetabolic pathway
PRIAMprofile
PDB structuresRCSB PDB PDBe PDBsum
Gene OntologyAmiGO / QuickGO

The 3 substrates of this enzyme are 3-aci-nitropropanoate, O2, and H2O, whereas its 3 products are 3-oxopropanoate, nitrite, and H2O2.

This enzyme belongs to the family of oxidoreductases, specifically those acting on other nitrogenous compounds as donors with oxygen as acceptor. The systematic name of this enzyme class is 3-aci-nitropropanoate:oxygen oxidoreductase. This enzyme is also called propionate-3-nitronate oxidase. It employs one cofactor, FMN.

References

    • Porter DJ, Bright HJ (1987). "Propionate-3-nitronate oxidase from Penicillium atrovenetum is a flavoprotein which initiates the autoxidation of its substrate by O2". J. Biol. Chem. 262 (30): 14428–34. PMID 3667582.
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