Ubiquitin carboxyl-terminal hydrolase L5

UCHL5
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases UCHL5, CGI-70, INO80R, UCH-L5, UCH37, Ubiquitin carboxyl-terminal hydrolase L5, ubiquitin C-terminal hydrolase L5
External IDs MGI: 1914848 HomoloGene: 9326 GeneCards: UCHL5
Genetically Related Diseases
cannabis dependence[1]
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

51377

56207

Ensembl

ENSG00000116750

ENSMUSG00000018189

UniProt

Q9Y5K5
Q5LJB0

Q9WUP7

RefSeq (mRNA)

NM_001199261
NM_001199262
NM_001199263
NM_015984

NM_001159866
NM_019562

RefSeq (protein)

NP_001186190.1
NP_001186191.1
NP_001186192.1
NP_057068.1

NP_001153338.1
NP_062508.2

Location (UCSC) Chr 1: 193.01 – 193.06 Mb Chr 1: 143.78 – 143.81 Mb
PubMed search [2] [3]
Wikidata
View/Edit HumanView/Edit Mouse

Ubiquitin carboxyl-terminal hydrolase isozyme L5 is an enzyme that in humans is encoded by the UCHL5 gene.[4][5][6]

References

  1. "Diseases that are genetically associated with UCHL5 view/edit references on wikidata".
  2. "Human PubMed Reference:".
  3. "Mouse PubMed Reference:".
  4. Lai CH, Chou CY, Ch'ang LY, Liu CS, Lin W (Aug 2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics". Genome Res. 10 (5): 703–13. doi:10.1101/gr.10.5.703. PMC 310876Freely accessible. PMID 10810093.
  5. Wicks SJ, Haros K, Maillard M, Song L, Cohen RE, Dijke PT, Chantry A (Dec 2005). "The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling". Oncogene. 24 (54): 8080–4. doi:10.1038/sj.onc.1208944. PMID 16027725.
  6. "Entrez Gene: UCHL5 ubiquitin carboxyl-terminal hydrolase L5".

Further reading


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