Thiorphan
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| Identifiers | |
|---|---|
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| CAS Number |
76721-89-6  N |
| PubChem (CID) | 3132 |
| DrugBank |
DB08626 N |
| ChemSpider |
3020  Y |
| UNII |
B79L7B5X3Z N |
| ChEMBL |
CHEMBL10247 Y |
| Chemical and physical data | |
| Formula | C12H15NO3S |
| Molar mass | 253.32 g/mol |
| 3D model (Jmol) | Interactive image |
| Chirality | Racemic mixture |
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| NY (what is this?) (verify) | |
Thiorphan is the active metabolite of the antidiarrheal racecadotril (acetorphan).[1] It prevents the degradation of endogenous enkephalins by acting as an enkephalinase inhibitor.[1]
See also
References
- 1 2 Spillantini MG, Geppetti P, Fanciullacci M, Michelacci S, Lecomte JM, Sicuteri F (June 1986). "In vivo 'enkephalinase' inhibition by acetorphan in human plasma and CSF". European Journal of Pharmacology. 125 (1): 147–50. doi:10.1016/0014-2999(86)90094-4. PMID 3015640.
| Rehydration | |
|---|---|
| Intestinal anti-infectives | |
| Intestinal adsorbents | |
| Antipropulsives (opioids) |
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| Intestinal anti-inflammatory agents |
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| Antidiarrheal micro-organisms | |
| Other antidiarrheals | |
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