Enterococcus faecium
| Enterococcus faecium | |
|---|---|
| Scientific classification | |
| Kingdom: | Bacteria |
| Phylum: | Firmicutes |
| Class: | Bacilli |
| Order: | Lactobacillales |
| Family: | Enterococcaceae |
| Genus: | Enterococcus |
| Species: | E. faecium |
| Binomial name | |
| Enterococcus faecium (Orla-Jensen 1919) Schleifer & Kilpper-Bälz 1984 | |
Enterococcus faecium is a Gram-positive, alpha-hemolytic or nonhemolytic bacterium in the genus Enterococcus.[1] It can be commensal (innocuous, coexisting organism) in the human intestine, but it may also be pathogenic, causing diseases such as neonatal meningitis or endocarditis.
Vancomycin-resistant E. faecium is often referred to as VRE.[2]
Some strains of E. faecium are used as probiotics in both animals[3] and humans.[4]
Genome sequences
Genomes listed below are from the Integrated Microbial Genomes website.
The 22 sequenced Enterococcus faecium genomes
| Strain | ST | CC17 | Country | Year |
|---|---|---|---|---|
| 1,231,408 | 582 | Yes | NA | NA |
| 1,231,501 | 52 | No | NA | NA |
| Com15 | 583 | No | USA (MA) | 2006 |
| 1,141,733 | 327 | No | NA | NA |
| 1,230,933 | 18 | Yes | NA | NA |
| 1,231,410 | 17 | Yes | NA | NA |
| 1,231,502 | 203 | Yes | NA | NA |
| Com12 | 107 | No | USA (MA) | 2006 |
Treatment
Linezolid or daptomycin is used to treat VRE infections. The streptogramins, such as quinupristin/dalfopristin, may also be used for VREs. VRE can be successfully treated with sultamicillin.[5]
References
- ↑ Ryan KJ, Ray CG (editors) (2004). Sherris Medical Microbiology (4th ed.). McGraw Hill. pp. 294–5. ISBN 0-8385-8529-9.
- ↑ Mascini EM, Troelstra A, Beitsma M, et al. (March 2006). "Genotyping and preemptive isolation to control an outbreak of vancomycin-resistant Enterococcus faecium". Clin. Infect. Dis. 42 (6): 739–46. doi:10.1086/500322. PMID 16477546.
- ↑ http://www.purinaveterinarydiets.com/Product/FortiFloraCatNutritionalSupplements.aspx
- ↑ Sisson, G.; Ayis, S.; Sherwood, RA.; Bjarnason, I. (Jul 2014). "Randomised clinical trial: A liquid multi-strain probiotic vs. placebo in the irritable bowel syndrome--a 12 week double-blind study.". Aliment Pharmacol Ther. 40 (1): 51–62. doi:10.1111/apt.12787. PMID 24815298.
- ↑ Chewning JH; et al. "Vancomycin resistant Enterococcus faecium bacteremia successfully treated with high dose ampicillin sulbactam in a pediatric patient after hematopoietic stem cell transplantation". J. Pediatr. Hematol. Oncol. 33: 401. doi:10.1097/MPH.0b013e31820db7eb. PMID 21602724.
Further reading
Sadowy, E; Luczkiewicz, A (14 March 2014). "Drug-resistant and hospital-associated Enterococcus faecium from wastewater, riverine estuary and anthropogenically impacted marine catchment basin.". BMC microbiology. 14: 66. doi:10.1186/1471-2180-14-66. PMID 24629030. Retrieved 12 November 2014.