Septum (cell biology)

Septins in Saccharomyces cerevisiae (fluorescent micrograph)
• Green: septins (AgSEP7-GFP)
• Red: cell outline (phase contrast)
• Scale bar: 10 μm

A septum in cell biology is the new cell wall that forms between two daughter cells during the telophase[1] of cell division.

In yeast, septins form a ring structure, to which other proteins are recruited.[2] In particular, chitinase 2 is required, an enzyme that synthesises chitin thereby building up the primary septum. A secondary septum of β-glucans and mannoproteins is then assembled, and the primary septum degraded during cell separation.[2][3]


  1. "Cell Division: Stages of Mitosis | Learn Science at Scitable". Retrieved 2015-11-16.
  2. 1 2 Cabib E; Roh DH; Schmidt M; Crotti LB; Varma A (2001). "The yeast cell wall and septum as paradigms of cell growth and morphogenesis". J. Biol. Chem. 276 (23): 19679–82. doi:10.1074/jbc.R000031200. PMID 11309404.
  3. Lesage G; Bussey H (2006). "Cell wall assembly in Saccharomyces cerevisiae". Microbiol. Mol. Biol. Rev. 70 (2): 317–43. doi:10.1128/MMBR.00038-05. PMC 1489534Freely accessible. PMID 16760306.

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