Sclerema neonatorum

Sclerema neonatorum
Classification and external resources
Specialty	pediatrics
ICD-10	P83.0
ICD-9-CM	778.1
DiseasesDB	31401
eMedicine	article/1112191
MeSH	D012593

Sclerema neonatorum is a rare and severe skin condition that is characterized by diffuse hardening of the subcutaneous tissue with minimal inflammation.^[1]^[2] It usually affects premature, ill newborns. Prognosis is poor.

Minimal inflammation helps distinguish sclerema neonaturum from subcutaneous fat necrosis of the newborn.

References

↑ James, William D.; Berger, Timothy G.; et al. (2006). Andrews' Diseases of the Skin: clinical Dermatology. Saunders Elsevier. p. 490. ISBN 0-7216-2921-0.
↑ Rapini, Ronald P.; Bolognia, Jean L.; Jorizzo, Joseph L. (2007). Dermatology: 2-Volume Set. St. Louis: Mosby. pp. 1515, 1524, 1525. ISBN 1-4160-2999-0.

Disorders of subcutaneous fat (M79.3, 729.3)

Panniculitis

Lobular	without vasculitis Cold Cytophagic histiocytic Factitial Gouty Pancreatic Traumatic needle-shaped clefts Subcutaneous fat necrosis of the newborn Sclerema neonatorum Post-steroid panniculitis Lipodermatosclerosis Weber–Christian disease Lupus erythematosus panniculitis Sclerosing lipogranuloma with vasculitis: Nodular vasculitis/Erythema induratum

Septal	without vasculitis: Alpha-1 antitrypsin deficiency panniculitis Erythema nodosum Acute Chronic with vasculitis: Superficial thrombophlebitis

Lipodystrophy

Acquired	generalized: Acquired generalized lipodystrophy partial: Acquired partial lipodystrophy Centrifugal abdominal lipodystrophy HIV-associated lipodystrophy Lipoatrophia annularis localized: Localized lipodystrophy

Congenital	Congenital generalized lipodystrophy Familial partial lipodystrophy Poland syndrome

Certain conditions originating in the perinatal period / fetal disease (P, 760–779)

Maternal factors and
complications of pregnancy,
labour and delivery

placenta:	Placenta praevia Placental insufficiency Twin-to-twin transfusion syndrome

chorion/amnion:	Chorioamnionitis

umbilical cord:	Umbilical cord prolapse Nuchal cord Single umbilical artery

Length of gestation
and fetal growth

Birth trauma

By system

Respiratory	Intrauterine hypoxia Infant respiratory distress syndrome Transient tachypnea of the newborn Meconium aspiration syndrome pleural disease Pneumothorax Pneumomediastinum Wilson–Mikity syndrome Bronchopulmonary dysplasia

Cardiovascular	Pneumopericardium Persistent fetal circulation

Haemorrhagic and hematologic disease	Vitamin K deficiency Haemorrhagic disease of the newborn HDN ABO Anti-Kell Rh c Rh D Rh E Hydrops fetalis Hyperbilirubinemia Kernicterus Neonatal jaundice Velamentous cord insertion Intraventricular hemorrhage Germinal matrix hemorrhage Anemia of prematurity

Digestive	Ileus Necrotizing enterocolitis Meconium peritonitis

Integument and thermoregulation	Erythema toxicum Sclerema neonatorum

Nervous system	Periventricular leukomalacia

Musculoskeletal	Gray baby syndrome muscle tone Congenital hypertonia Congenital hypotonia

Infectious

Other

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Sclerema neonatorum

See also

References