SYT7

SYT7
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
Aliases SYT7, IPCA-7, IPCA7, PCANAP7, SYT-VII, SYTVII, synaptotagmin 7
External IDs MGI: 1859545 HomoloGene: 20889 GeneCards: SYT7
Orthologs
Species Human Mouse
Entrez

9066

54525

Ensembl

ENSG00000011347

ENSMUSG00000024743

UniProt

O43581

Q9R0N7

RefSeq (mRNA)

NM_001252065
NM_001300773
NM_004200

NM_018801
NM_173067
NM_173068

RefSeq (protein)

NP_001238994.1
NP_001287702.1
NP_004191.2

NP_061271.1
NP_775090.1
NP_775091.2

Location (UCSC) Chr 11: 61.52 – 61.58 Mb Chr 19: 10.39 – 10.45 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Synaptotagmin-7 is a protein that in humans is encoded by the SYT7 gene.[3][4]

Function

Synaptotagmins, such as SYT7, are brain-specific calcium-dependent phospholipid-binding proteins that play a role in synaptic exocytosis and neurotransmitter release. See MIM 600782.[supplied by OMIM][4]

Interactions

SYT7 has been shown to interact with SYNCRIP.[5]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Cooper PR, Nowak NJ, Higgins MJ, Church DM, Shows TB (May 1998). "Transcript mapping of the human chromosome 11q12-q13.1 gene-rich region identifies several newly described conserved genes". Genomics. 49 (3): 419–29. doi:10.1006/geno.1998.5291. PMID 9615227.
  4. 1 2 "Entrez Gene: SYT7 synaptotagmin VII".
  5. Mizutani A, Fukuda M, Ibata K, Shiraishi Y, Mikoshiba K (March 2000). "SYNCRIP, a cytoplasmic counterpart of heterogeneous nuclear ribonucleoprotein R, interacts with ubiquitous synaptotagmin isoforms". The Journal of Biological Chemistry. 275 (13): 9823–31. doi:10.1074/jbc.275.13.9823. PMID 10734137.

Further reading

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