SUPT6H

Identifiers

SUPT6H, SPT6, SPT6H, emb-5, SPT6 homolog, histone chaperone

External IDs

MGI: 107726 HomoloGene: 40661 GeneCards: SUPT6H

Gene ontology
Molecular function	• DNA binding • transcription factor activity, sequence-specific DNA binding • histone binding • protein binding • nucleic acid binding • poly(A) RNA binding
Cellular component	• nucleus
Biological process	• chromatin remodeling • negative regulation of histone H3-K27 methylation • mRNA transport • regulation of transcription, DNA-templated • regulation of muscle cell differentiation • regulation of mRNA export from nucleus • regulation of mRNA processing • regulation of transcription from RNA polymerase II promoter • mRNA processing • regulation of DNA-templated transcription, elongation • transcription, DNA-templated • RNA splicing • transport • regulation of isotype switching • viral process • nucleobase-containing compound metabolic process • positive regulation of transcription elongation from RNA polymerase II promoter
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse

Entrez


6830


20926

Ensembl


ENSG00000109111


ENSMUSG00000002052

UniProt


Q7KZ85


Q62383

RefSeq (mRNA)


NM_003170 NM_001320755


NM_009297

RefSeq (protein)


NP_003161.2 NP_001307684.1


NP_033323.2

Location (UCSC)

Chr 17: 28.66 – 28.7 Mb

Chr 11: 78.21 – 78.25 Mb

PubMed search

^[1]

^[2]

Wikidata

View/Edit Human

View/Edit Mouse

Transcription elongation factor SPT6 is a protein that in humans is encoded by the SUPT6H gene.^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Chiang PW, Wang S, Smithivas P, Song WJ, Ramamoorthy S, Hillman J, Puett S, Van Keuren ML, Crombez E, Kumar A, Glover TW, Miller DE, Tsai CH, Blackburn CC, Chen XN, Sun Z, Cheng JF, Korenberg JR, Kurnit DM (Sep 1996). "Identification and analysis of the human and murine putative chromatin structure regulator SUPT6H and Supt6h". Genomics. 34 (3): 328–33. doi:10.1006/geno.1996.0294. PMID 8786132.
↑ "Entrez Gene: SUPT6H suppressor of Ty 6 homolog (S. cerevisiae)".

Andersson B, Wentland MA, Ricafrente JY, et al. (1996). "A "double adaptor" method for improved shotgun library construction.". Anal. Biochem. 236 (1): 107–13. doi:10.1006/abio.1996.0138. PMID 8619474.
Nagase T, Seki N, Ishikawa K, et al. (1996). "Prediction of the coding sequences of unidentified human genes. V. The coding sequences of 40 new genes (KIAA0161-KIAA0200) deduced by analysis of cDNA clones from human cell line KG-1.". DNA Res. 3 (1): 17–24. doi:10.1093/dnares/3.1.17. PMID 8724849.
Yu W, Andersson B, Worley KC, et al. (1997). "Large-scale concatenation cDNA sequencing.". Genome Res. 7 (4): 353–8. doi:10.1101/gr.7.4.353. PMC 139146. PMID 9110174.
Chiang PW, Stubbs L, Zhang L, Kurnit DM (1998). "Isolation of murine SPT5 homologue: completion of the isolation and characterization of human and murine homologues of yeast chromatin structural protein complex SPT4, SPT5, and SPT6.". Genomics. 47 (3): 426–8. doi:10.1006/geno.1997.5137. PMID 9480761.
Wu-Baer F, Lane WS, Gaynor RB (1998). "Role of the human homolog of the yeast transcription factor SPT5 in HIV-1 Tat-activation.". J. Mol. Biol. 277 (2): 179–97. doi:10.1006/jmbi.1997.1601. PMID 9514752.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Endoh M, Zhu W, Hasegawa J, et al. (2004). "Human Spt6 stimulates transcription elongation by RNA polymerase II in vitro.". Mol. Cell. Biol. 24 (8): 3324–36. doi:10.1128/MCB.24.8.3324-3336.2004. PMC 381665. PMID 15060154.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.

This article is issued from Wikipedia - version of the 6/3/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.

SUPT6H

References

Further reading