RyeB RNA

SdsR/RyeB RNA
Predicted secondary structure and sequence conservation of SdsR_RyeB
Identifiers
Symbol SdsR_RyeB
Rfam RF00111
Other data
RNA type Gene; sRNA
Domain(s) Bacteria
SO 0000655

The SdsR/RyeB RNA is a non-coding RNA that was identified in a large scale screen of E. coli.[1] The exact 5' and 3' ends of this RNA are uncertain. This RNA overlaps the SraC/RyeA RNA on the opposite strand suggesting that the two may act in a concerted manner. It is transcribed by general stress factor σs and is most highly expressed in stationary phase. SdsR/RyeB RNA interacts with Hfq.

The homologous sRNA in S. enterica was shown to regulate synthesis of major porin OmpD.[2] A study using Salmonella identified 20 targets of this sRNA including transcriptional regulator, CRP, global DNA-binding factors, StpA and HupB, the antibiotic transporter protein, TolC, and the RtsA/B two-component system (TCS), and validated their post-transcriptional control by SdsR/RyeB RNA.[3]

See also

References

  1. ↑ Wassarman, KM; Repoila F; Rosenow C; Storz G; Gottesman S (2001). "Identification of novel small RNAs using comparative genomics and microarrays". Genes Dev. 15 (13): 1637–1651. doi:10.1101/gad.901001. PMC 312727Freely accessible. PMID 11445539.
  2. ↑ Fröhlich, Kathrin S.; Papenfort, Kai; Berger, Allison A.; Vogel, Jörg (2012-04-01). "A conserved RpoS-dependent small RNA controls the synthesis of major porin OmpD". Nucleic Acids Research. 40 (8): 3623–3640. doi:10.1093/nar/gkr1156. ISSN 1362-4962. PMC 3333887Freely accessible. PMID 22180532.
  3. ↑ Fröhlich, Kathrin S.; Haneke, Katharina; Papenfort, Kai; Vogel, Jörg (2016-07-12). "The target spectrum of SdsR small RNA in Salmonella". Nucleic Acids Research. doi:10.1093/nar/gkw632. ISSN 1362-4962. PMID 27407104.

External links

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