Receptor tyrosine kinase-like orphan receptor

receptor tyrosine kinase-like orphan receptor 1
Identifiers
Symbol	ROR1
Alt. symbols	NTRKR1
Entrez	4919
HUGO	10256
OMIM	602336
RefSeq	NM_005012
UniProt	Q01973
Other data
EC number	2.7.10.1
Locus	Chr. 1 p32-p31

receptor tyrosine kinase-like orphan receptor 2
Identifiers
Symbol	ROR2
Alt. symbols	NTRKR2, BDB, BDB1
Entrez	4920
HUGO	10257
OMIM	602337
RefSeq	NM_004560
UniProt	Q01974
Other data
Locus	Chr. 9 q22

In the field of molecular biology, receptor tyrosine kinase-like orphan receptors (RORs) are a family of tyrosine kinase receptors that are important in regulating skeletal and neuronal development, cell migration and cell polarity. ROR proteins can modulate Wnt signaling by sequestering Wnt ligands.^[1]

References

↑ Green JL, Kuntz SG, Sternberg PW (November 2008). "Ror receptor tyrosine kinases: orphans no more". Trends Cell Biol. 18 (11): 536–44. doi:10.1016/j.tcb.2008.08.006. PMID 18848778.

EGF receptor family	EGFR ERBB2 ERBB3 ERBB4

Insulin receptor family	IGF1R INSR INSRR

PDGF receptor family	CSF1R FLT3 KIT PDGFR (PDGFRA PDGFRB)

FGF receptor family	FGFR1 FGFR2 FGFR3 FGFR4

VEGF receptors family	VEGFR1 VEGFR2 VEGFR3

HGF receptor family	MET RON

Trk receptor family	NTRK1 NTRK2 NTRK3

ROS receptor family

uncategorised

Enzymes

Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Catalytically perfect enzyme Coenzyme Cofactor Enzyme catalysis Enzyme kinetics Lineweaver–Burk plot Michaelis–Menten kinetics

Regulation	Allosteric regulation Cooperativity Enzyme inhibitor

Classification	EC number Enzyme superfamily Enzyme family List of enzymes

Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list)

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