ProteomeXchange

ProteomeXchange is a consortium of proteomics data repositories that aims to enhance the usability and interoperability of independent resources by streamlining the submission and discovery of datasets across those resources.[1]

History

The earliest conception of ProteomeXchange stems from a meeting at the HUPO 2005 conference in Munich,[2] where the main proteomics data repositories at the time agreed in principle to exchange their data, and thus provide a means for the user to find public proteomics data at any of the participating databases. In early times the name was written with a capital E (ProteomExchange), but then later (and currently) the X is capitalized (ProteomeXchange) instead. ProteomeXchange began to become reality in an HPP meeting in Barbados in 2009 where Lennart Martens, Eric Deutsch, and Phil Andrews agreed on a set of deliverables and registered the proteomexchange.org domain. ProteomeXchange was then fully developed through the 'ProteomeXchange' Coordination Action grant of the European Commission's Seventh Framework Programme (project reference 260558).

Members

The current active members of ProteomeXchange are:

  1. Proteomics Identifications Database (PRIDE)
  2. PeptideAtlas
  3. MassIVE

Current Status

The ProteomeXchange consortium and web sites are actively maintained by its member organizations. Explicit funding for the consortium has ended, but the system continues in maintenance mode, with minimal changes, until new funding is obtained to enable further progress.

References

  1. ↑ Vizcaíno, JA; Deutsch, EW; Wang, R; Csordas, A; Reisinger, F; Ríos, D; Dianes, JA; Sun, Z; Farrah, T; Bandeira, N; Binz, PA; Xenarios, I; Eisenacher, M; Mayer, G; Gatto, L; Campos, A; Chalkley, RJ; Kraus, HJ; Albar, JP; Martinez-Bartolomé, S; Apweiler, R; Omenn, GS; Martens, L; Jones, AR; Hermjakob, H (March 2014). "ProteomeXchange provides globally coordinated proteomics data submission and dissemination.". Nature Biotechnology. 32 (3): 223–6. doi:10.1038/nbt.2839. PMID 24727771.
  2. ↑ Hermjakob, H; Apweiler, R (February 2006). "The Proteomics Identifications Database (PRIDE) and the ProteomExchange Consortium: making proteomics data accessible.". Expert review of proteomics. 3 (1): 1–3. doi:10.1586/14789450.3.1.1. PMID 16445344.
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