PARP10

PARP10
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
Aliases PARP10, ARTD10, poly(ADP-ribose) polymerase family member 10
External IDs MGI: 3712326 HomoloGene: 53133 GeneCards: PARP10
Orthologs
Species Human Mouse
Entrez

84875

671535

Ensembl

ENSG00000178685

ENSMUSG00000063268

UniProt

Q53GL7

n/a

RefSeq (mRNA)

NM_032789
NM_001317895

NM_001163575
NM_001163576

RefSeq (protein)

NP_116178.2

n/a

Location (UCSC) Chr 8: 143.98 – 144.01 Mb Chr 15: 76.23 – 76.24 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Poly [ADP-ribose] polymerase 10 is an enzyme that in humans is encoded by the PARP10 gene.[3][4]

Poly(ADP-ribose) polymerases (PARPs), such as PARP10, regulate gene transcription by altering chromatin organization by adding ADP-ribose to histones. PARPs can also function as transcriptional cofactors (Yu et al., 2005).[supplied by OMIM][4]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Ame JC, Spenlehauer C, de Murcia G (Jul 2004). "The PARP superfamily". BioEssays. 26 (8): 882–93. doi:10.1002/bies.20085. PMID 15273990.
  4. 1 2 "Entrez Gene: PARP10 poly (ADP-ribose) polymerase family, member 10".

Further reading


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