OR3A3

OR3A3
Identifiers
Aliases OR3A3, OR17-137, OR17-16, OR17-201, OR3A6, OR3A7, OR3A8P, olfactory receptor family 3 subfamily A member 3
External IDs MGI: 3030245 HomoloGene: 74999 GeneCards: OR3A3
RNA expression pattern
More reference expression data
Orthologs
Species Human Mouse
Entrez

8392

258704

Ensembl

ENSG00000159961

ENSMUSG00000054406

UniProt

P47888

n/a

RefSeq (mRNA)

NM_012373

NM_146709

RefSeq (protein)

NP_036505.2

n/a

Location (UCSC) Chr 17: 3.42 – 3.42 Mb Chr 11: 74.35 – 74.35 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Olfactory receptor 3A3 is a protein that in humans is encoded by the OR3A3 gene.[3][4][5]

Function

Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms.[5]

See also

References

  1. ↑ "Human PubMed Reference:".
  2. ↑ "Mouse PubMed Reference:".
  3. ↑ Ben-Arie N, Lancet D, Taylor C, Khen M, Walker N, Ledbetter DH, Carrozzo R, Patel K, Sheer D, Lehrach H (Jul 1994). "Olfactory receptor gene cluster on human chromosome 17: possible duplication of an ancestral receptor repertoire". Hum Mol Genet. 3 (2): 229–35. doi:10.1093/hmg/3.2.229. PMID 8004088.
  4. ↑ Rouquier S, Taviaux S, Trask BJ, Brand-Arpon V, van den Engh G, Demaille J, Giorgi D (Mar 1998). "Distribution of olfactory receptor genes in the human genome". Nat Genet. 18 (3): 243–50. doi:10.1038/ng0398-243. PMID 9500546.
  5. 1 2 "Entrez Gene: OR3A3 olfactory receptor, family 3, subfamily A, member 3".

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.


This article is issued from Wikipedia - version of the 5/20/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.