Nuclear mitotic apparatus protein 1

NUMA1
Available structures
PDBHuman UniProt search: PDBe RCSB
Identifiers
Aliases NUMA1, NUMA, NMP-22, nuclear mitotic apparatus protein 1
External IDs MGI: 2443665 HomoloGene: 38150 GeneCards: NUMA1
RNA expression pattern


More reference expression data
Orthologs
Species Human Mouse
Entrez

4926

101706

Ensembl

ENSG00000137497

ENSMUSG00000066306

UniProt

Q14980
Q3SYK8

n/a

RefSeq (mRNA)

NM_001286561
NM_006185

NM_133947

RefSeq (protein)

NP_001273490.1
NP_006176.2
NP_006176.2

n/a

Location (UCSC) Chr 11: 72 – 72.08 Mb Chr 7: 101.97 – 102.01 Mb
PubMed search [1] [2]
Wikidata
View/Edit HumanView/Edit Mouse

Nuclear mitotic apparatus protein 1 is a protein that in humans is encoded by the NUMA1 gene.[3][4]

Interactions

Nuclear mitotic apparatus protein 1 has been shown to interact with PIM1,[5] Band 4.1,[6] GPSM2[7] and EPB41L1.[8]

References

  1. "Human PubMed Reference:".
  2. "Mouse PubMed Reference:".
  3. Sparks CA, Bangs PL, McNeil GP, Lawrence JB, Fey EG (Oct 1993). "Assignment of the nuclear mitotic apparatus protein NuMA gene to human chromosome 11q13". Genomics. 17 (1): 222–224. doi:10.1006/geno.1993.1307. PMID 8406455.
  4. "Entrez Gene: NUMA1 nuclear mitotic apparatus protein 1".
  5. Bhattacharya, Nandini; Wang Zeping; Davitt Christine; McKenzie Ian F C; Xing Pei-Xiang; Magnuson Nancy S (Jul 2002). "Pim-1 associates with protein complexes necessary for mitosis". Chromosoma. Germany. 111 (2): 80–95. doi:10.1007/s00412-002-0192-6. ISSN 0009-5915. PMID 12111331.
  6. Mattagajasingh, S N; Huang S C; Hartenstein J S; Snyder M; Marchesi V T; Benz E J (Apr 1999). "A nonerythroid isoform of protein 4.1R interacts with the nuclear mitotic apparatus (NuMA) protein". J. Cell Biol. UNITED STATES. 145 (1): 29–43. doi:10.1083/jcb.145.1.29. ISSN 0021-9525. PMC 2148212Freely accessible. PMID 10189366.
  7. Du, Q; Stukenberg P T; Macara I G (Dec 2001). "A mammalian Partner of inscuteable binds NuMA and regulates mitotic spindle organization". Nat. Cell Biol. England. 3 (12): 1069–1075. doi:10.1038/ncb1201-1069. ISSN 1465-7392. PMID 11781568.
  8. Ye, K; Compton D A; Lai M M; Walensky L D; Snyder S H (Dec 1999). "Protein 4.1N binding to nuclear mitotic apparatus protein in PC12 cells mediates the antiproliferative actions of nerve growth factor". J. Neurosci. UNITED STATES. 19 (24): 10747–56. PMID 10594058.

Further reading


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