Nitrofural

Nitrofural
Clinical data


AHFS/Drugs.com	Micromedex Detailed Consumer Information
Pregnancy category	US: C (Risk not ruled out)
ATC code	B05CA03 (WHO) D08AF01 (WHO) D09AA03 (WHO) (dressing) P01CC02 (WHO) S01AX04 (WHO) S02AA02 (WHO) QG01AX90 (WHO) QP51AC02 (WHO)
Identifiers
IUPAC name (2E)-2-[(5-Nitro-2-furyl)methylene]hydrazine carboxamide
CAS Number	59-87-0^Y
PubChem (CID)	5447130
DrugBank	DB00336^Y
ChemSpider	4566720^Y
UNII	X8XI70B5Z6^Y
KEGG	C08042^N
ChEBI	CHEBI:44368
ChEMBL	CHEMBL869^Y
ECHA InfoCard	100.000.403
Chemical and physical data
Formula	C₆H₆N₄O₄
Molar mass	198.14 g/mol
3D model (Jmol)	Interactive image
SMILES O=[N+]([O-])c1oc(/C=N/NC(=O)N)cc1
InChI InChI=1S/C6H6N4O4/c7-6(11)9-8-3-4-1-2-5(14-4)10(12)13/h1-3H,(H3,7,9,11)/b8-3+^Y Key:IAIWVQXQOWNYOU-FPYGCLRLSA-N^Y
^NY (what is this?) (verify)

Nitrofural (INN, trade name Furacin) is a bactericidal compound used as an antibiotic most commonly in the form of ointments. Its use in medicine has become less frequent as safer and more effective products have become available, and it has been discontinued in the US.^[1] The substance is pale yellow and crystalline.

Other names include nitrofurazone and furacilin.

Drugstore-made ~400 mL aqueous solution of Furacilin (nitrofural), 1 : 5000 (0.2 mg/mL or 0.02%), ready for topical use.

References

↑ Drugs.com: Nitrofurazone (Topical route)

Antiparasitics – antiprotozoal agents – Chromalveolate antiparasitics (P01)

Alveo-
late

Apicom-
plexa

Conoidasida/
(Coccidiostats)

Cryptosporidiosis	thiazolides (nitazoxanide)

Isosporiasis	trimethoprim/sulfamethoxazole^#

Toxoplasmosis	pyrimethamine sulfadiazine

Aconoidasida

Malaria

Individual
agents

Hemozoin
inhibitors

Aminoquinolines	(4-): amodiaquine^# chloroquine^# hydroxychloroquine^# (8-): primaquine^# pamaquine^‡ tafenoquine^†

4-Methanolquinolines	mefloquine^# quinine^# quinidine

Other	lumefantrine + artemether^# halofantrine

Antifolates

DHFR inhibitors	pyrimethamine biguanides chlorproguanil proguanil^#

Sulfonamides	sulfadoxine sulfalene

Co-formulation	sulfadoxine/pyrimethamine (SP)^#

Sesquiterpene
lactones

Other

Combi-
nations

Fixed-dose (co-formulated) ACTs	artemether/lumefantrine^# arterolane/piperaquine artesunate/amodiaquine (ASAQ) artesunate/mefloquine (ASMQ) artesunate/pyronaridine dihydroartemisinin/piperaquine

Other combinations (not co-formulated)	artesunate/mefloquine artesunate/SP quinine/clindamycin quinine/doxycycline quinine/tetracycline

Babesiosis

clindamycin

Cilio-
phora

Balantidiasis: tetracycline

Hetero-
kont

Blastocystosis: metronidazole

^#WHO-EM
^‡Withdrawn from market
Clinical trials:
- ^†Phase III
- ^§Never to phase III

Drugs used for diseases of the ear (S02)

Infection	Acetic acid Aluminium acetotartrate Aluminium triacetate (Burow's solution) Boric acid Chloramphenicol Chlorhexidine Ciprofloxacin Clioquinol Gentamicin Hydrogen peroxide Miconazole Neomycin Nitrofurazone Ofloxacin Polymyxin B Rifamycin Tetracycline

Corticosteroids	Betamethasone Dexamethasone Fluocinolone acetonide Hydrocortisone Prednisolone

Analgesics and anesthetics	Lidocaine Cocaine Phenazone

This article is issued from Wikipedia - version of the 11/7/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.