Monopolin
| Monopolin complex subunit CSM1 | |
|---|---|
| Identifiers | |
| Organism | |
| Symbol | CSM1 |
| Entrez | 850447 |
| RefSeq (mRNA) | NM_001178792 |
| RefSeq (Prot) | NP_010009 |
| UniProt | P25651 |
| Other data | |
| Chromosome | III: 0.26 - 0.26 Mb |
| Casein kinase I homolog HRR25 | |
|---|---|
| Identifiers | |
| Organism | |
| Symbol | HRR25 |
| Entrez | 855897 |
| RefSeq (mRNA) | NM_001184018 |
| RefSeq (Prot) | NP_015120 |
| UniProt | P29295 |
| Other data | |
| EC number | 2.7.11.1 |
| Chromosome | XVI: 0.16 - 0.17 Mb |
| Monopolin complex subunit LRS4 | |
|---|---|
| Identifiers | |
| Organism | |
| Symbol | LRS4 |
| Entrez | 852049 |
| RefSeq (mRNA) | NM_001180747 |
| RefSeq (Prot) | NP_010727 |
| UniProt | Q04087 |
| Other data | |
| Chromosome | IV: 1.34 - 1.34 Mb |
| Monopolin complex subunit MAM1 | |
|---|---|
| Identifiers | |
| Organism | |
| Symbol | MAM1 |
| Entrez | 856843 |
| RefSeq (mRNA) | NM_001178997 |
| RefSeq (Prot) | NP_011032 |
| UniProt | P40065 |
| Other data | |
| Chromosome | V: 0.37 - 0.37 Mb |
Monopolin is a protein complex that in yeast is composed of the four proteins CSM1, HRR25, LRS4, and MAM1. Monopolin is required for the segregation of homologous centromeres to opposite poles of a dividing cell during anaphase I of meiosis.[1]
References
- ↑ Corbett KD, Yip CK, Ee LS, Walz T, Amon A, Harrison SC (August 2010). "The monopolin complex crosslinks kinetochore components to regulate chromosome-microtubule attachments". Cell. 142 (4): 556–67. doi:10.1016/j.cell.2010.07.017. PMC 2955198
. PMID 20723757.
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