Mepivacaine

Mepivacaine
Clinical data
AHFS/Drugs.com Consumer Drug Information
MedlinePlus a603026
Pregnancy
category
  • C, use w/ caution, may cause fetal bradycardia
ATC code N01BB03 (WHO)
Identifiers
CAS Number 96-88-8 YesY
PubChem (CID) 4062
IUPHAR/BPS 7224
DrugBank DB00961 YesY
ChemSpider 3922 YesY
UNII B6E06QE59J YesY
KEGG D08181 YesY
ChEBI CHEBI:6759 YesY
ChEMBL CHEMBL1087 YesY
ECHA InfoCard 100.002.313
Chemical and physical data
Formula C15H22N2O
Molar mass 246.348 g/mol
3D model (Jmol) Interactive image
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Mepivacaine /mɛˈpɪvəkn/ is a local anesthetic[1] of the amide type. Mepivacaine has a reasonably rapid onset (more rapid than that of procaine) and medium duration of action (shorter than that of procaine) and is marketed under various trade names including Carbocaine and Polocaine.

Mepivacaine became available in the United States in the 1960s.

Mepivacaine is used in any infiltration and regional anesthesia.

It is supplied as the hydrochloride salt of the racemate, [2] which consists of R(-)-mepivacaine and S(+)-mepivacaine in equal proportions. These two enantiomers have markedly different pharmacokinetic properties. [3]

References


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