MPHOSPH8

MPHOSPH8

Available structures

Ortholog search: PDBe RCSB

List of PDB id codes
3LWE, 3QO2, 3R93, 3SVM

Identifiers

MPHOSPH8, HSMPP8, TWA3, mpp8, M-phase phosphoprotein 8

External IDs

MGI: 1922589 HomoloGene: 11380 GeneCards: MPHOSPH8

Gene ontology
Molecular function	• methylated histone binding • protein binding • ubiquitin protein ligase binding • ubiquitin-protein transferase activity
Cellular component	• cytoplasm • nuclear heterochromatin • nuclear nucleosome • plasma membrane • nucleolus • extracellular exosome • nucleus • chromosome • ubiquitin ligase complex
Biological process	• regulation of DNA methylation • negative regulation of transcription, DNA-templated • regulation of transcription, DNA-templated • transcription, DNA-templated • protein ubiquitination
Sources:Amigo / QuickGO

RNA expression pattern

More reference expression data

Orthologs

Species

Human

Mouse


54737


75339


ENSG00000196199


ENSMUSG00000079184


Q99549


Q3TYA6

RefSeq (mRNA)


NM_017520


NM_023773

RefSeq (protein)


NP_059990.2


NP_076262.2

Location (UCSC)

Chr 13: 19.63 – 19.67 Mb

Chr 14: 56.67 – 56.7 Mb

PubMed search

^[1]

^[2]

View/Edit Human

View/Edit Mouse

M-phase phosphoprotein 8 is an enzyme that in humans is encoded by the MPHOSPH8 gene.^[3]^[4]

References

↑ "Human PubMed Reference:".
↑ "Mouse PubMed Reference:".
↑ Matsumoto-Taniura N, Pirollet F, Monroe R, Gerace L, Westendorf JM (Jan 1997). "Identification of novel M phase phosphoproteins by expression cloning". Mol Biol Cell. 7 (9): 1455–69. doi:10.1091/mbc.7.9.1455. PMC 275994. PMID 8885239.
↑ "Entrez Gene: HSMPP8 M-phase phosphoprotein, mpp8".

Further reading

Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983.
Maksimov VV, Arman IP, Tarantul VZ (2006). "[Identification of the proteins interacting with neuroprotective peptide humanin in a yeast two-hybrid system]". Genetika. 42 (2): 274–7. PMID 16583711.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Dunham A, Matthews LH, Burton J, et al. (2004). "The DNA sequence and analysis of human chromosome 13.". Nature. 428 (6982): 522–8. doi:10.1038/nature02379. PMC 2665288. PMID 15057823.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs.". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Umeda M, Nishitani H, Nishimoto T (2003). "A novel nuclear protein, Twa1, and Muskelin comprise a complex with RanBPM.". Gene. 303: 47–54. doi:10.1016/S0378-1119(02)01153-8. PMID 12559565.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.

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