Louis Lewin

Louis Lewin (born in Tuchel, West Prussia, 9 November 1850; died 1 December 1929 in Berlin) was a German pharmacologist. In 1887 he received his first sample of the Peyote cactus from Dallas, Texas-based physician Joseph Raleigh Briggs (1851-1907), and later published the first methodical analysis it, causing a variant to be named Anhalonium lewinii in his honor.[1] Lewin received his education at the gymnasium and the University of Berlin (M.D. 1876). The two years following his graduation he spent at Munich, in the laboratories of von Voit and Pettenkofer. Returning to Berlin in 1878, he became an assistant at the pharmacological institute of the university, and in 1881 he was admitted to the medical faculty as Privatdozent. In 1897 he was finally appointed professor.[2]

Louis Lewin's book "Die Nebenwirkungen der Arzneimittel" (1881) deals with the borderline between the pharmacological and the toxicological action of drugs with the untoward or side-effects of all kinds of medicaments.[3] It was the first book of its kind.[2] Another of his important books was "Phantastica" (1924),[4] which began an era of ethnobotany that continues to the present day.

Lewin mentioned in his book "Gifte und Vergiftungen" (1929) the causal connection between dental amalgam fillings and illness.[5] One of his famous patients were the well-known chemistry professor Alfred Stock (1876-1946), who suffered from mercury poisoning due to occupational exposure.[5] Lewin informed him also about mercury exposure from dental amalgams. In 1926 in an article in Zeitschrift für Angewandte Chemie (Journal of Applied Chemistry), Stock claimed that released mercury from amalgam fillings caused poisoning and demanded the consumption stopped.[6] This triggered a sharp and intense debate in Germany.[7]

In Berlin, a street and the nearby underground train station were named in honour of Louis Lewin.

Drug classification

One of Lewin's most enduring tasks was to create a system of classification of psychoactive drugs and plants based on their pharmacologic action. His original categories were:

Works

Lewin was a prolific writer. Among his many essays may be mentioned:

Lewin is also the author of the following books:

References

  1. www.druglibrary.org
  2. 1 2 Macht DI. Louis Lewin: pharmacologist, toxicologist, medical historian. Ann Med Hist 1931; 3: 179–194.
  3. Lewin L. Die Nebenwirkungen der Arzneimittel. Pharmakologisch-klinisches Handbuch. Berlin: August Hirschwald Verlag, 1881.
  4. Lewin L. Phantastica. Die betäubenden und erregenden Genussmittel. Für Ärzte und Nichtärzte. Berlin: Verlag von Georg Stilke, 1924.
  5. 1 2 Lewin L. Gifte und Vergiftungen. Berlin: Verlag von Georg Stilke, 1929.
  6. Stock A. Die Gefährlichkeit des Quecksilberdampfes. Z Angew Chem 1926; 15: 461-466. English translation.
  7. Bjørklund G. The history of dental amalgam (in Norwegian). Tidsskr Nor Laegeforen 1989; 109: 3582-3585.

External links

 This article incorporates text from a publication now in the public domain: Singer, Isidore; et al., eds. (1901–1906). "article name needed". Jewish Encyclopedia. New York: Funk & Wagnalls Company. 

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