List of people from the Pittsburgh metropolitan area

• Betty Aberlin (Allegheny) – active 1975–2004
• Julie Benz (Allegheny) – active 1990–present
• Barbara Bosson (Washington) – active 1968–97
• Lori Cardille (Allegheny) – active 1975–89
• Joan Chandler (Butler) – active 1944–60
• Rhoda Chase (Fayette)
• Caitlin Clarke (Allegheny) – active 1981–2002
• Dolores Costello (Allegheny) – active 1909–43
• Marpessa Dawn (Allegheny) – active 1957–96
• Joyce Ebert
• Sandra Ferguson (Allegheny) – active 1987–2009
• Barbara Feldon (Allegheny) – active 1969–
• Bette Ford (Allegheny) – active 1977–2003
• Monica Lee Gradischek (Westmoreland) – active 1994–
• Gillian Jacobs
• Sam Jenkins (Allegheny)
• Cherie Johnson (Allegheny)
• Angela Jones (Westmoreland)
• Shirley Jones (Westmoreland)
• Melina Kanakaredes
• Sheila Kelley (Westmoreland) – active 1987–present
• Lisa Kirk (Washington)
• Christine Laitta (Allegheny)
• Heather Mazur (Allegheny)
• Mitzi McCall
• Judith McConnell
• Frances McDormand (Westmoreland)
• Kitty McHugh (Butler)
• Ming-Na (Allegheny)
• Demi Moore (Westmoreland)
• Anisha Nagarajan (Allegheny)
• Evelyn Nesbit
• Lillian Peacock (Westmoreland)
• Katelyn Pippy (Allegheny)
• Natalie Raitano (Westmoreland)
• Margot Rose (Allegheny)
• Zelda Rubinstein
• Lillian Russell
• Rena Sofer (Allegheny)
• Lauren Tewes (Allegheny)
• Olive Thomas (Washington)
• Tamara Tunie
• Julia Warhola (Allegheny)
• Organist, Arthur Nobile, Jr. (Westmoreland)

Actors

• Laman Rucker

Comedians

Reporters and anchors

Media personalities

Producers, directors, and effects

Music

Jazz, soul, R&B, and gospel

Classics and standards

Rock and alternative

Country and folk

Pop

Rap and hip-hop

Dancers and choreographers

• Sharon Needles – drag queen, winner of RuPaul's Drag Race (season 4)
• Eddie Adams (Westmoreland) – portrait photographer for the stars
• Matt Baker (Allegheny) – comic book artist
• Romare Bearden (Allegheny)
• Seddon Bennington (Allegheny)
• Randy Bish (Armstrong)
• Ailsa Mellon Bruce – Mellon heir and art patron
• Charles Joseph Carter (Lawrence) – magician
• Mary Cassatt (Allegheny) – artist
• Terry Deglau (Westmoreland) – photographer
• Vito Delsante (Armstrong) – comic artist
• Angelo Donghia (Westmoreland)
• Harold H. Fisher (Fayette)
• Keith Haring – artist
• Charles "Teenie" Harris – photographer
• Jerry Harris – sculptor
• Yvonne Jacquette – painter and printmaker
• Michael Lotenero (Allegheny) – painter and sculptor
• Craig McCracken (Washington) – illustrator
• Scott McDaniel (Allegheny) – comic book artist
• James Michalopoulos (Allegheny) – painter and sculptor^[5]
• Duane Michals (Allegheny) – photographer
• Burton Morris – artist
• Thaddeus Mosley – sculptor
• Jackie Ormes (Washington)
• Philip Pearlstein (Allegheny) – painter
• Robert Qualters (Allegheny) – painter
• Lawrence Saint – stained glass artist
• Naomi Sims (Allegheny) – model
• William Louis Sonntag, Sr. – painter
• George Sotter (Allegheny) – painter
• Gertrude Stein (Allegheny) – artist
• Renee Stout (Allegheny) – multi-media artist
• Andy Warhol (Allegheny) – painter
• Julia Warhola (Allegheny)
• Scott Warner (Westmoreland) – lighting designer
• Bruce Weber (Westmoreland) – photographer
• Greg Wright (Lawrence) – comic artist
• Bunny Yeager – photographer, supermodel and bikini pioneer

• Joseph Bathanti (Allegheny) – poet, writer, professor; NC Poet Laureate, 2012–2014
• Gérard Bessette (Allegheny) – writer, professor
• Richard Blevins (Allegheny) – poet
• Nellie Bly (Allegheny) – Pulitzer Prize-winning investigative journalist and writer
• Kenneth Burke (Allegheny) – literary theorist
• John Dickson Carr (Fayette) – crime novelist
• Michael Chabon – Pulitzer Prize-winning author
• Murray Chass – New York Times baseball writer, author
• Stephen Chbosky – author
• K. C. Constantine (Westmoreland) – author
• Malcolm Cowley (Allegheny) – poet, critic
• Melanie Craft – novelist; wife of Larry Ellison of Oracle
• Stephen Dau – writer
• Rebecca Harding Davis (Washington) – 19th-century author
• Margaret Deland (Allegheny) – novelist
• Annie Dillard – author and Pulitzer Prize winner
• Jack Gilbert (Allegheny) – poet
• Beth Gylys poet and professor
• Kerry Hannon author
• Terence Hawkins (Fayette) – short-story writer
• David Leavitt – novelist
• Stephen Manes – magazine writer, author

David Scott Milton - novelist, playwright, screenwriterP

• David McCullough – historian and author and two-time Pulitzer Prize winner
• Burton Morris – painter
• Marie Hochmuth Nichols (Fayette) – critic
• Peter Oresick (Allegheny) – poet
• Tamora Pierce (Fayette) – fantasy writer
• Mary Roberts Rinehart – mystery writer
• Gladys Schmitt (Allegheny) – writer
• May French Sheldon (Beaver) – publisher
• Jim Shooter – comic book writer, editor and publisher
• James Sites – novelist
• George Smith (Allegheny) – gambler, handicapper
• Gertrude Stein – writer, poet, playwright, and feminist
• Gerald Stern – poet
• Kathleen Tessaro – novelist
• Agnes Sligh Turnbull (Westmoreland) – author
• Joseph Wambaugh – crime novelist
• John Edgar Wideman – author and professor
• August Wilson – Pulitzer Prize-winning playwright
• Brandon Wilson – travel writer

• Bill Bishop (Westmoreland)
• Bill Blair (Allegheny)
• John Burkett (Beaver)
• Dave Bush (Pittsburgh)^[6]
• Matt Clement (Butler)
• Tim Conroy (Allegheny) – 1978–87
• Bruce Dal Canton (Washington)
• Matt DeSalvo (Lawrence)
• Bill Doak (Allegheny) – Cardinals and Dodgers, inventor of the modern baseball glove
• Bill Ford (Allegheny)
• Bob Galasso (Fayette) – 1977–81
• Pud Galvin (Allegheny) – 1875–92, Hall of Fame
• Bob Garber (Westmoreland) – 1950s
• Mark Grater (Beaver) – 1991–93
• Clay Hamilton (Beaver) – 2004–
• Ed Hobaugh (Armstrong) – 1961–63
• Brian Holton (Allegheny) – 1985–90
• Zach Jackson (Westmoreland) – 2006–present
• Ron Kline (Butler)
• Rick Krivda (Allegheny) – 1995–98
• Curt Leskanic (Allegheny)
• George "Doc" Medich (Beaver) – Pittsburgh Pirates
• Tom McCreery (Beaver) – 1895–1905, three inside-the-park homers in one game
• Sam McDowell
• Roger Miller (Fayette) – 1970s
• Rudy Minarcin (Armstrong)
• Bob Moose (Westmoreland)
• Terry Mulholland (Fayette)
• Ron Necciai (Washington) – struck out 27 in one game
• Scott Patterson (Allegheny)
• Chris Peters (Allegheny) – 1996–2001
• Tim Plodinec (Beaver)
• John Pyecha (Beaver) – 1954
• Tom Qualters (Allegheny) – 1953–58
• Ed Roebuck (Fayette) – 1955–66
• Josh Sharpless (Beaver)
• Steve Sundra (Westmoreland) – 1936–46
• Steve Swetonic (Westmoreland) – 1929–35
• John K. Tener (Allegheny) – 1885–90, NL president and governor
• John Tudor (Allegheny) – World Series-winning pitcher 1979–90
• Joe Vitelli (Allegheny) – 1940s
• Frances Vukovich (Allegheny) – AAGPL 1940s
• Dixie Walker (Fayette) – pitcher 1908–12; father of two major leaguers

• Ed Abbaticchio (Westmoreland) – infielder 1897–1910, won a World Series with the Pirates
• Dick Allen (Lawrence) – 1963–77
• Ron Allen (Lawrence) – first baseman 1972
• Bob Bailor (Fayette) – utility fielder 1975–85
• Glenn Beckert (Allegheny) – second baseman (from Shaler)
• Buddy Bell (Allegheny) – third baseman (1972–89)
• Charlie Bennett (Lawrence) – 1878–93
• Sid Bream (Allegheny) – 1983–94; originally from Carlisle, makes his home in Allegheny County
• Sean Casey (Allegheny) – retired first baseman (Upper St. Clair High School)
• Buster Clarkson (Westmoreland)
• Betty Jane Cornett (1932–2006) – third base (1950–1952) All-American Girls Professional Baseball League
• Al Federoff (Allegheny) – second baseman 1951–52
• Bob Garbark (Allegheny) – catcher 1934–45
• Ryan Garko (Allegheny) – first baseman Giants
• Gary Green (Allegheny)
• Khalil Greene (Butler) – shortstop Cardinals
• Dick Groat (Allegheny) – shortstop, National League Most Valuable Player, 1960
• Howdy Groskloss (Allegheny) – shortstop 1930–32; oldest living MLB player
• Bobby Lowe (Allegheny) – second baseman 1890–1907
• Bill Mazeroski – second baseman, only player ever to decide a World Series by a 7th game home run
• Michael Robert "Mickey" Morandini (Armstrong) – second baseman (1990–2000)
• Jack Onslow (Westmoreland) – catcher 1912–17
• Lance Parrish (Allegheny) – catcher 1977–1995
• Marguerite Pearson (Tesseine) (Hazelwood) – utility player 1948–1954, All-American Girls Professional Baseball League
• Ted Reed (Beaver) – 1910s
• Curt Roberts (Beaver) – second baseman, Pittsburgh Pirates; first African-American for Pirate organization, 1954–1957
• Rich Rollins (Westmoreland) – second baseman 1961–70
• Joe Schepner (Beaver)
• Paul Smith (Lawrence) – first baseman 1953–1958
• Pete Suder (Beaver) – infielder 1941–55
• Harold Joseph "Pie" Traynor – Pirates Hall of Fame member
• Butts Wagner (Allegheny) – 1898
• Honus Wagner (Allegheny) – shortstop, Hall of Fame member
• Neil Walker (Allegheny) – second baseman for the New York Mets
• John Wehner – Pirates infielder, broadcaster
• Josh Wilson (Allegheny) – 2005–present

• Hank Allen (Lawrence) – 1966–73
• Ollie Carnegie (Allegheny) – 1931–45
• Bob Coulson (Washington) – 1908–1914
• Jack Damaska (Beaver) – player for St. Louis, Minor League manager
• Doc Gessler (Westmoreland) – 1903–11
• Josh Gibson (Allegheny) – Negro League player, Pittsburgh Crawfords and Homestead Grays
• Andy Gilbert (Westmoreland) – 1942–46
• Bob Gorinski (Westmoreland) – 1970s
• Ken Griffey, Jr. (Washington) – 1989–2010
• Ken Griffey, Sr. (Washington) – 1973–91, World Series
• Don Kelly (Butler) – 2007–
• Bobby Lowe (Allegheny) – first MLB player with 4 home runs in a game^[7]
• Stan Musial (Washington) – outfielder 1941–1963, World Series, Baseball Hall of Fame
• Jimmy Ripple (Westmoreland) – outfielder 1936–1943, 1940 World Series champion
• Bill Robinson (Allegheny) – 1966–83
• Heinie Smith (Allegheny)^[7]
• John Stuper (Butler) – MLB player, Yale University coach
• Danny Taylor (Westmoreland) – 1926–36
• Bobby Wallace (Allegheny) – Hall of Fame inductee^[7]
• Hack Wilson (Beaver) – outfielder, Hall of Fame member

• Bill Armour (Allegheny) – Indians, Tigers 1902–06
• Buddy Bell (Allegheny) – 1996–2007 managed Tigers, Rockies and Royals
• Ollie Carnegie (Allegheny) – 1944
• Terry Francona (Beaver) – managed Indians, Phillies and 2004 World Series champion Red Sox
• Art Howe (Allegheny) – managed Astros and A's
• Jim Leyland (Allegheny) – native since 1986; managed Pirates, Marlins, Rockies and Tigers
• Joe Lonnett (Beaver) – coach for White Sox, A's, Pirates
• Ken Macha (Allegheny) – A's 2003–06, Brewers 2009–10
• Bill McKechnie (Allegheny) – 1922–46 managed Pirates, Reds and Cardinals, 3x World Series
• Jack Onslow (Westmoreland) – managed White Sox 1949–50
• Rick Peterson (Allegheny) – pitching coach 1998–
• Chuck Tanner (Lawrence) – managed Pittsburgh Pirates, Braves and White Sox
• Harold Joseph "Pie" Traynor Pittsburgh Pirates, Hall of Fame member
• Honus Wagner (Allegheny) – Hall of Fame member

• Peter Angelos (Allegheny) – Baltimore Orioles owner
• Bill Benswanger (Allegheny) – Pirates owner, vocal advocate for integration
• Barney Dreyfuss (Allegheny) – Pirates owner, inventor of the World Series
• Chuck Greenberg (Allegheny) – Rangers former owner
• Gus Greenlee (Allegheny) – Crawfords founder
• John P. Harris (Allegheny) – Boston Braves owner
• Ray Kennedy (Allegheny) – scout and GM
• Tony LaCava (Allegheny) – longtime scout and assistant general manager
• Larry Lucchino (Allegheny) – Red Sox owner, team's first title in 90 years
• Jerry Meals (Butler) – umpire
• Cumberland Posey (Allegheny) – Grays founder
• John L. Rice (Allegheny) – AL umpire 1955–73, 3 ASG's, 1959 World Series
• John K. Tener (Allegheny) – NL president, later governor
• Ed Vargo (Butler) – NL umpire 1960–83
• Thomas Zacharias (Allegheny) – umpire
• Jack Zduriencik (Lawrence) – Mariners GM

• Dick Bennett (Allegheny) – Wisconsin, Washington State 1976–2006
• Paul Birch (Allegheny)
• Eddie Cameron (Allegheny) – Duke 1929–49 until 1972, Cameron Indoor Stadium, founding member of the ACC, football coach and Olympic selector

• Chick Davies (Lawrence)
• Ed DeChellis (Beaver)
• Scott Edgar (Allegheny)
• Elmer Gross (Allegheny) – PSU 1950–54
• Buddy Jeannette (Westmoreland) – NBA 1947–67, ABA 1969–70
• George Karl (Allegheny) – over 1,000 NBA wins with Bucks, Sonics and Nuggets 1984–
• Press Maravich (Beaver) – 1949–75 NC State, Clemson and LSU
• Suzie McConnell-Serio (Allegheny) – WNBA player 1998–2000, head coach 2004–06, Duquesne 2007–
• Archie Miller (Beaver) – Dayton 2011–
• Sean Miller (Beaver) – Xavier 2003–09, Arizona 2009–
• Dudey Moore (Allegheny)
• Skip Prosser (Allegheny) – Loyola (MD), Xavier, and Wake Forest 1993–2007
• Mike Rice, Sr. (Allegheny)
• Mike Rice, Jr. (Allegheny)
• Charles Ridl (Westmoreland)
• Will Robinson (Allegheny) – first African-American head coach for a Division I team
• Herb Sendek (Allegheny) – NC State and Arizona State 1994–
• C. Vivian Stringer (Fayette) – Rutgers women's basketball coach, Hall of Fame

• John Abramovic – 1946–48
• DeJuan Blair – Pitt All-American, Spurs 2009–13, Mavericks 2013–
• Barney Cable (Beaver) – 1958–67
• Swin Cash – WNBA 2002–
• Chuck Cooper – 1950–56; first drafted African-American
• Ken Durrett (Allegheny) – 1971–75 NBA
• Dave Feitl – 1986–92
• Danny Fortson – SuperSonics, Bucks
• Armen Gilliam – 1987–2000
• George Glamack – 1948–49
• Paul Grant – 1997–2004
• Simmie Hill (Beaver) – 1970s
• Stew Johnson – 1966–76
• Billy Knight – 1975–85
• Maurice Lucas – 1975–88
• Walt Miller – 1946–47
• Barry Nelson – 1971–72
• Dave Piontek – 1956–63 NBA
• Maurice Stokes – Rochester/Cincinnati Royals 1955–58; Hall of Famer
• Walt Szczerbiak (Allegheny) – 1971–72 NBA
• Dennis Wuycik (Beaver) – 1972–75 NBA

• Jim Baechtold (Allegheny) – 1952–57
• Moe Barr – 1970–71 NBA
• Paul Birch (Allegheny)
• Myron Brown (Allegheny) – 1991–92 NBA
• Ron Carter (Allegheny) – 1978–80 NBA
• Claire Cribbs (Westmoreland)
• Brad Davis (Beaver) – 1977–92
• Mickey Davis (Beaver) – 1971–77 NBA
• Calvin Fowler – 1969–70
• Jack George – 1953–61
• Gus Gerard (Fayette) – 1977–81
• Dick Groat – 1952–53, baseball player
• Mike Iuzzolino – 1991–93
• Buddy Jeannette – 1948–70, NBA Hall of Fame
• DeAndre Kane (Allegheny)
• George Karl – 1973–78, head coach 1984–, NBA Finals
• Stu Lantz – 1968–76
• Freddie Lewis – ABA 1960s–70s, co-owner of Xplosion
• Pete Maravich (1947–1988) – Hall of Famer; guard 1971–80, all-time NCAA Division I men's scoring leader
• Jack Marin – 1966–77
• T. J. McConnell – Arizona Wildcats and Philadelphia 76ers
• Sean Miller (Beaver) – head coach at Xavier (2004–09) and Arizona (2009–present)
• Johnny Moore – 1979–90
• Geoff Petrie – 1970–76
• Wilbert Robinson (Fayette) – 1973–74 NBA
• Ron Rowan (Beaver) – 1986–87
• Willie Somerset – 1966–69
• Jack Twyman – 1955–66, Hall of Famer
• Tanisha Wright (Allegheny)

• Mark Cuban (Allegheny) – Mavericks owner
• Tim Grgurich (Allegheny) – Pitt coach
• Red Mihalik (Armstrong) – guard 1947–48, longtime NBA referee
• Ted Stepien – Cavs former owner
• Sonny Vaccaro – shoe company exec

• Sammy Angott (Washington) – welterweight Hall of Famer
• Bob Baker (Washington) – heavyweight contender
• Charley Burley (Lawrence) – middleweight, 83-12-2 record
• George Chip (Lawrence) – middleweight champ 1913
• Billy Conn (Allegheny) – light-heavyweight champ 1939–41
• Andy DePaul (Allegheny) – middleweight contender, referee
• Harry Greb (Allegheny) – middleweight champ 1923
• Frank Klaus (Allegheny) – middleweight champ 1904
• Paul Komar (Allegheny) – heavyweight champ 1943
• Brian Minto (Butler) – cruiserweight contender
• Michael Moorer (Westmoreland) – heavyweight champ 1992–93, 1994, 1996–97
• Frank Moran (Allegheny) – fought twice for heavyweight title
• Homer Robertson (Allegheny) – middleweight champion 1923
• Billy Soose (Mercer) – middleweight champ, 1941
• Paul Spadafora (Allegheny) – lightweight champ, 1999
• Leo Sweeny (Allegheny) – welterweight champ 1936
• Jackie Wilson (Allegheny) – featherweight champ, early 1900s (decade)
• Teddy Yarosz (Allegheny) – middleweight champ, 1934
• Fritzie Zivic (Allegheny) – welterweight champ, 1940

• Suna Murray – 1972 Winter Olympian, mother of Kylie Gleason
• Ronald "Ronnie" Robertson – silver medalist at 1956 Winter Olympics
• Michael Seibert – five-time gold medalist at U.S. Figure Skating Championships; three bronze medals at World Championships
• Suzanne Semanick – ice dancing, 1988 Winter Olympics, coach and choreographer
• Jamie Silverstein – ice dancing
• Taylor Toth – pairs skating

• Joe Bugel (Allegheny) – assistant and head coach 1975–present; founder of the "Hogs" of the 1980s
• Bud Carson (Allegheny) – assistant (four Super Bowls) and head coach of Cleveland Browns
• Bill Cowher (Allegheny) – Steelers head coach 1992–2007, Super Bowl champion
• Mike Ditka (Beaver) – tight end (1961–72), head coach Chicago Bears, New Orleans Saints (1982–99), three Super Bowls
• Luke Getsy (Allegheny)
• Mike Getto (Westmoreland) – 1940s
• Todd Haley (Allegheny) – Steelers offensive coordinator, Kansas City Chiefs head coach 2009–11
• Jim Haslett (Butler) – head coach Saints (2000–2005), Rams D.C. (2006–08)
• Ernie Hefferle (Westmoreland) – Boston College in 1960s, New Orleans Saints in 1970s
• Chuck Knox (Allegheny) – Rams, Bills and Seahawks
• Marvin Lewis (Washington) – head coach of Cincinnati Bengals
• Bob Ligashesky (Allegheny) – assistant 2004–present
• Mike McCarthy (Allegheny) – Packers head coach 2005–present
• Herb McCracken (Allegheny) – college 1920s and 1930s
• Scott McCurley (Lawrence) – Packers
• John Michelosen (Beaver) – 1940s–1960s
• Mike Miller (Allegheny) – assistant 1999–present
• Dick Nolan (Allegheny) – head coach, San Francisco 49ers and New Orleans Saints
• Willis Richardson (Allegheny)
• Nick Saban – college football 1990, 1995–2004, 2007–present; NFL assistant, 1991–1994; NFL head coach 2005–2006 (born in Fairmont, West Virginia)
• Kurt Schottenheimer (Allegheny)
• Marty Schottenheimer (Allegheny) – 1984–present, head coach of 4 NFL teams
• Jim Tomsula (Allegheny) – 49ers head coach 2015–present
• Jim Trimble (Allegheny) – 1950s
• Frank Walton (Beaver)
• Joe Walton (Beaver) – head coach Jets 1981–89 and RMU 1994–present; offensive coordinator for Redskins and Steelers 1993–2004
• Dave Wannstedt (Allegheny) – head coach, Pitt, Chicago Bears, Miami Dolphins
• Mike Westhoff (Allegheny) – assistant 1984–present
• Woody Widenhofer (Butler) – NFL and NCAA assistant

• Barry Alvarez (Washington) – Wisconsin head coach (1990–2005, interim for 2013 Rose Bowl); Wisconsin athletic director, 2004–present
• Teryl Austin (Mercer) – Florida
• Dick Bestwick – 1971 Marshall, 1976–81 Virginia
• Curtis Bray (Allegheny) – assistant
• Harold Burry (Lawrence) – College Football Hall of Fame
• Frank Cignetti, Jr. (Allegheny) – Rutgers
• Bob Davie (Allegheny) – former Notre Dame head coach
• Tom Davies (Beaver) – 1922–47
• Joseph Duff (Allegheny) – Pitt football coach; died in action in World War I
• Earle Edwards (Westmoreland) – NC State Head Coach 1954–70, ACC Coach of the Year
• Kirk Ferentz (Allegheny) – University of Iowa
• Jimbo Fisher – Florida State (from Clarksburg, West Virginia)
• Joe Fusco (Allegheny) – Westminster 1972–90
• Vic Fusia (Allegheny) – assistant Pitt 1955–60; head coach UMass 1961–70
• Pete Henry (Washington)
• Lou Holtz – college football 1969–2004; former Notre Dame head coach
• Nick Kotys (Westmoreland) – 4 national and 6 state titles, Coral Gables HS 1950s–1970s
• Frank Kush (Cambria) – Arizona State 1958–79
• Rich Lackner – Carnegie Mellon 1986–
• Mark Mangino (Lawrence) – former University of Kansas head coach
• Mike Milligan (Beaver) – 1940s
• Mike Nixon (Fayette) – 1960s–1980s
• Larry Pugh (Lawrence) – College Football Hall of Fame
• Joe Rudolph (Washington)
• Jerry Sandusky (Washington) – Assistant of the Year 1986, 1999, defensive coordinator PSU 1977–99; later convicted of multiple counts of child sex abuse
• Joe Thompson (Allegheny) – Pitt coach, Hall of Famer, World War I Medal of Honor winner

• Charlie Batch (Allegheny)
• Todd Blackledge – 1988–89
• Eddie Blair (Westmoreland)
• George Blanda (Westmoreland) – 1949–75, Super Bowl, Hall of Fame
• John Brallier (Allegheny)
• Marc Bulger (Allegheny) – 2000–2011, Super Bowl^[8]
• Ed Chlebek (Fayette) – 1960s, college head coach
• Daryll Clark (Westmoreland)
• Tom Clements
• Paul Failla (Allegheny) – 1999–2001
• Bernie Faloney (Allegheny) – 1954–67 CFL
• Gus Frerotte (Armstrong) – 1994–2009
• Chuck Fusina (Allegheny) – NFL 1979–86
• Arnold Galiffa (Washington) – 1953–56
• Bruce Gradkowski (Allegheny) – Buccs, Raiders 2006–
• Terry Hanratty (Butler) – 1969–76, 2 Super Bowls
• Major Harris (Allegheny) – record-setter in college and CFL
• Leon Hart (Allegheny) – Heisman Trophy, College Hall of Fame
• Harold Hess (Fayette)
• Jeff Hostetler (Somerset) – 1- 985–97, two Super Bowls
• Frank Hudson (Allegheny) – 1895–96
• John Hufnagel (Allegheny) – NFL 1973–75 CFL 1976–87
• Al Jacks (Allegheny)
• Jim Kelly (Armstrong) – 1986–96, Hall of Fame, four Super Bowls
• Ron Lancaster (Allegheny) – CFL 1960–78
• Richie Lucas (Allegheny) – NFL 1960–62
• Johnny Lujack (Fayette) – Heisman Trophy (1947)
• Ted Marchibroda (Venango) – 1953–57, head coach 1975–98
• Dan Marino (Allegheny) – 1983–99, Hall of Fame, Super Bowl
• Coley McDonough (Allegheny) – NFL 1939–44
• Mike McMahon (Allegheny) – 2001–present
• Scott Milanovich (Butler) – NFL QB 1996–2003
• Joe Montana (Washington) – quarterback 1979–94, Hall of Fame, four Super Bowls, three Super Bowl MVPs
• Anthony Morelli (Allegheny)
• Joe Namath (Beaver) – 1965–77, Hall of Fame, Super Bowl MVP
• Dick Nolan (Allegheny) – Giants, Cowboys and Cardinals
• Tyler Palko (Allegheny)
• Babe Parilli (Beaver) – Super Bowl winner
• Frank Patrick (Westmoreland) – Green Bay 1970–72
• Terrell Pryor (Westmoreland)
• Rod Rutherford (Allegheny) – 2003–present
• Chad Salisbury (Fayette) – 2000–07 All-American
• Matt Schaub (Allegheny) – 2004–present
• George Shaffer (Westmoreland) – 1933
• Tom Sherman (Allegheny) – 1968–70 WFL/CFL 1971–76
• Sandy Stephens (Fayette) – quarterback; first African-American to lead his team to a bowl game
• Harry Theofiledes (Allegheny) – 1960s
• Willie Thrower (Westmoreland) – first African-American QB in an NFL game
• Johnny Unitas (Beaver) – 1956–73, Hall of Famer, two Super Bowls
• Alex Van Pelt (Allegheny) – 1995–2003
• Mark Vlasic (Beaver) – 1987–94
• Adam Wyant (Westmoreland) – Pro QB 1895–97
• Scott Zolak (Washington) – 1991–99 Super Bowl appearance

• Bill Amos – All-American W&J in the 1920s
• Kevan Barlow (Allegheny)
• Tony Benjamin (Westmoreland) – 1977–79
• Ernie Bonelli (Allegheny) – 1940s
• Jim Braxton (Fayette) – 1971–78, Bills and Dolphins
• Larry Brown (Allegheny) – Redskins, 1972 NFL MVP
• Jim Cunningham (Fayette) – 1960s
• Ernie Davis (Fayette) – Heisman Trophy (1961)
• Tony Dorsett (Beaver) – Heisman Trophy (1976) 1977–88, two Super Bowls
• Doug Dressler (Beaver) – 1970–75
• Bill Dutton – 1940s
• Cookie Gilchrist – AFL and CFL
• Joe Glamp (Westmoreland) – 1940s
• Walt Gorinski (Westmoreland) – 1940s
• Sam Havrilak (Westmoreland) – 1969–74 Super Bowl
• Warren Heller (Allegheny) – 1930s
• Dick Hoak (Westmoreland) – 1961–70
• Max Kielbasa (Fayette) – 1940s
• Hugh Knox (Allegheny)
• William F. Knox (Allegheny)
• Leo Koceski (Fayette)
• Roger Kochman (Allegheny) – 1963
• Doug Kotar (Washington)
• Martin Kottler (Allegheny) – 1930s
• Tim Manoa (Allegheny) – 1987–91
• Joe Marconi (Washington) – 1956–66 for the Rams, Bears
• Curtis Martin (Allegheny) – 1995–2006, Super Bowl
• Harry McChesney (Allegheny) – 1900s (decade) NFL
• Elmer Merkovsky (Allegheny) – 1940s
• Eugene "Mercury" Morris (Allegheny) – 70s Dolphins; two Super Bowls
• Chuck Muncie (Fayette) – Saints (1976–80) and Chargers (1981–84), 3 Pro Bowls
• Will Norman (Allegheny) – 1920s
• Lousaka Polite (Allegheny) – first three-year captain in Pitt history, Dolphins
• John Popovich (Westmoreland) – 1940s
• Billy Reynolds – 1950s and 1960s; attended Pitt
• Bo Scott (Fayette) – 1965–74
• Mike Sebastian (Westmoreland) – 1930s
• Rushel Shell (Beaver) – high school standout
• Frank Sinkwich (Allegheny) – 1943–47, first Heisman winner from SEC
• Frank Spaniel (Westmoreland) – 1950s
• Shawntae Spencer (Allegheny) – 49ers
• Travis Thomas (Washington) – 2008–
• Joe Wiehl (Washington) – 1930s
• Quincy Wilson – 2004–present
• Ray Zellars (Allegheny) – Saints, Oliver HS coach

• Danny Abramowicz (Jefferson) – wide receiver for Saints, 49ers
• Eugene Baker (Allegheny) – 1999–2004 NFL
• Jon Baldwin (Beaver) – 2011–present NFL
• Brian Baschnagel (Allegheny) – originally a running back, Ohio State, Bears 1976–1984
• Jim Beirne (Allegheny) – 1968–76 NFL
• Sean Berton (Westmoreland) – tight end 2003–2005
• Steve Breaston (Allegheny) – wide receiver/returner for Arizona Cardinals
• Nate Byham (Venango) – NFL tight end, 2000s (decade)
• Eric Crabtree (Westmoreland) – NFL receiver in the 1966–1971
• Bill Daddio (Crawford) – NFL end in the 1930s and 1940s
• Julius Dawkins (Westmoreland) – NFL receiver in the 1980s
• Dorin Dickerson (Allegheny) – NFL receiver in the 2000s (decade)
• Darnell Dinkins (Allegheny) – NFL tight end in the 1990s and 2000s (decade)
• Bobby Engram (Westmoreland) – NFL receiver 1996–2010, moved to the area during his playing career
• John Frank – NFL tight end in the 1980s
• Gregg Garrity – Penn State, NFL 1983–89
• Ken Herock (Allegheny) – NFL tight end 1963–69, Super Bowl
• Val Jansante (Fayette) – NFL receiver 1946–1951
• Tony Jeter (Jefferson)
• Ted Kwalick (Allegheny) – three-time Pro Bowl tight end for 49ers and Raiders; College Football Hall of Fame
• Bob Long (Allegheny) – 1964–70 NFL
• Brandon Marshall (Allegheny) – NFL wide receiver 2006–present
• Rasheed Marshall (Allegheny) – NFL wide receiver 2005–present
• Fred Mazurek (Fayette) – NFL receiver in the 1960s
• Paul McKee (Beaver) – tight end in the 1940s
• Bill Miller (Allegheny) – 1962–68 AFL
• Jim Mutscheller (Beaver) – tight end 1954–1961
• Bill Walker (Allegheny)
• Joel Williams – NFL tight end, 1987

• Rudy Andabaker (Washington) – NFL guard in the 1950s
• Charley Brueckman (Allegheny) – NFL center in the 1960s
• Dean Caliguire (Allegheny) – NFL lineman in 1991
• Jeff Christy (Armstrong) – three-time Pro Bowl center for Vikings and Buccaneers; Super Bowl ring
• Joe Cibulas (Westmoreland) – offensive lineman 1940s
• Richard Coulter, Jr. (Westmoreland) – lineman 1894–1896
• Jim Covert (Westmoreland) – offensive tackle for Chicago Bears, Super Bowl and 80s All-Decade Team
• Doug Crusan (Westmoreland) – offensive lineman 1968–1974, three Super Bowls
• Jack Davis (Allegheny) – 1960 AFL
• Damon Denson (Beaver) – guard 1996–2000
• Darrell Dess (Lawrence) – 1958–69
• Bill Fralic (Allegheny) – offensive lineman for Atlanta Falcons, '80s All-Decade Team
• Russ Freeman (Allegheny) – 1992–95 NFL
• Mitch Frerotte (Armstrong) – 1987–1993; holds NFL record for touchdowns in a season by a lineman (3)
• Ralph Fritz (Westmoreland) – guard 1940s
• Gary Greaves AFL tackle 1960
• Russ Grimm (Westmoreland) – offensive lineman 1981–91, three Super Bowls
• Buzz Guy (Lawrence) – NFL lineman 1958–1961
• Cal Jones (Jefferson) – Iowa player killed in plane crash
• Leander Jordan (Allegheny) – offensive lineman Carolina Panthers, San Diego Chargers, Atlanta Falcons, Jacksonville Jaguars
• Stan Keck (Westmoreland) – offensive lineman 1890s–1910s
• Mose Lantz NFL center 1933
• Jim MacMurdo (Beaver) – NFL lineman in the 1930s
• Baptiste Manzini (Allegheny) – NFL 1944–1948
• John Mastrangelo (Westmoreland) – NFL 1947–1950
• William R. Moore (Beaver) – NFL guard in the 1940s
• Dan Mozes (Washington) – center
• George Mrkonic (Allegheny) – NFL tackle in 1950s
• Lance Nimmo (Lawrence) – 2003–05
• Joe Palumbo (Beaver) – NFL guard in the 1950s
• Bull Polisky NFL guard 1929
• Frank Ribar (Fayette) – NFL guard 1940–1943, Washington Redskins
• Tom Ricketts (Allegheny) – NFL tackle 1980s and 1990s
• Mike Roussos (Lawrence) – NFL tackle in the 1940s
• Joe Rudolph (Washington) – NFL guard 1995–97
• Jack Sack (Allegheny) – NFL guard in the 1920s
• Alex Sandusky (Allegheny) – NFL guard 1954–66
• A. Q. Shipley (Allegheny) – NFL 2009–present
• Sean Stopperich (Washington) – All-American who blew the whistle on SMU, leading to NCAA "Death Penalty"^[9]
• Joe Stydahar (Cambria) – tackle 1936–46; Hall of Fame
• Keith Van Horne (Allegheny) – lineman 1981–93 NFL; Super Bowl winner
• Frank Walton (Beaver) – NFL tackle in the 1940s
• Reggie Wells (Allegheny) – tackle 2003–2012; Arizona Cardinals 2003–2009, 2010 Philadelphia, 2011 Carolina, 2012 San Diego
• Brian Williams (Allegheny) – 1989–99 NFL
• John Wozniak (Westmoreland) – NFL lineman 1948–1956
• Andy Wyant (Armstrong) – center, 1890s
• Frank Wydo (Fayette) – NFL offensive and defensive lineman 1947–1957

• Mike Barnes (Allegheny) – Pro Bowler 1973–1981
• Nick Bolkovac (Allegheny) – NFL lineman in the 1950s
• Bob Buczkowski (Allegheny) – NFL defensive end in the 1980s
• Bird Carroll (Westmoreland) – NFL end 1920s
• Sam Clancy (Allegheny) – NFL defensive end in the 1980s and 1990s
• Bruce Clark (Lawrence) – 1980–91
• Ave Daniell (Allegheny) – NFL tackle in the 1930s
• Aaron Donald (Allegheny) – NFL defensive tackle
• Nick Drahos (Armstrong) – NFL end in 1940s
• Jack Dugger – NFL lineman 1946–49
• Tory Epps (Fayette) – tackle 1990–2002
• Sean Gilbert (Beaver) – defensive end 1992–2005
• Art Gob (Allegheny) – NFL defensive end, 1950s and 1960s
• Jeff Hartings – defensive lineman with Penn State and Pittsburgh Steelers 2001–06, Detroit 1996–2001
• George Hays (Allegheny) – NFL 1950–52
• Cameron Heyward (Allegheny) – NFL 2011–present
• Randy Holloway (Mercer) – NFL defensive end 1970s and 1980s
• Stan Jones (Blair) – defensive lineman 1954–66, Hall of Fame
• David Logan (Allegheny) – defensive tackle 1970s and 1980s
• Ed Loucks (Westmoreland) – end 1920s
• Pete Marcus (Westmoreland) – end 1940s
• Bill McPeak (Lawrence) – NFL defensive end in the 1950s
• Greg Meisner (Westmoreland) – NFL lineman 1980s and 1990s
• Ron Nery (Westmoreland) – NFL defensive end 1960–1963
• Jack O'Brien (Westmoreland) – NFL end 1954–1956
• Fred Shirey (Westmoreland) – NFL lineman in the 1940s
• Leo Skladany – NFL defensive end 1940s and 1950s
• Andy Stynchula (Westmoreland) – NFL lineman 1960–1968
• Jason Taylor (Allegheny) – defensive end; five-time Pro Bowler for Miami Dolphins
• Steve Uhrinyak (Allegheny) – NFL 1930s
• Al Wesbecher (Westmoreland) – tackle 1916–1920
• Randy White (Allegheny) – defensive lineman 1975–88; three Super Bowls, Hall of Fame
• Leo Wisniewski (Allegheny) – NFL 1982–1984
• Frank Wydo (Fayette) – NFL offensive and defensive lineman 1947–1957

• LaVar Arrington (Allegheny) – NFL linebacker 2000–06
• Greg Best (Beaver) – NFL safety 1983–1984
• Jack Butler (Allegheny) – cornerback 1951–59, Pro Football Hall of Fame
• Walt Corey (Westmoreland) – NFL linebacker 1960–1966
• Anthony Dorsett (Beaver) – NFL safety 1990s and 2000s
• Ralph Felton (Washington) – NFL linebacker 1954–1962
• Jim Flanigan, Sr. (Allegheny) – NFL linebacker 1960s and 1970s
• Tom Flynn (Allegheny) – NFL safety in the 1980s
• Bill George (Greene) – linebacker 1952–66, Hall of Fame
• Don Graham Penn State, NFL 1987–89
• Kirby Griffin (Beaver) – linebacker 2009–present
• Kris Griffin (Beaver) – linebacker 2005–present
• Dick Haley (Washington) – cornerback for the Redskins, Vikings and Steelers
• Jack Ham (Cambria) – linebacker 1970–82, Hall of Fame, four Super Bowls
• Daven Holly (Allegheny) – NFL cornerback 2005–08
• Sam Huff – linebacker 1956–69, Hall of Fame
• Mortty Ivy (Allegheny) – NFL linebacker
• Justin King (Allegheny) – NFL 2008–present
• Ty Law (Beaver) – defensive back 1995–2005; four Super Bowls
• Josh Lay (Beaver) – NFL cornerback 2000s (decade)
• Sean Lee (Upper St Clair) – linebacker for Dallas Cowboys
• Maurice Leggett (Allegheny) – NFL 2008–11
• George Little (Duquesne) – NFL Miami Dolphins 1985–1987; CFL Montreal Machine 1991–1992
• Mike Logan (Allegheny) – NFL safety 1996–2006, Super Bowl
• Paul Martha (Allegheny) – NFL safety in the 1960s
• Dick McCabe (Allegheny) – NFL safety in the 1950s and 1960s
• Scott McKillop (Allegheny) – linebacker for Pitt and San Francisco 49ers
• Kevin "Boo" McLee – linebacker
• Rich Milot (Allegheny) – NFL 1979–87; three Super Bowls
• Robert Mitinger (Westmoreland) – linebacker for Penn State and the San Diego Chargers in the 1960s
• Ryan Mundy (Allegheny) – NFL safety
• Jerry Olsavsky – NFL linebacker 1980s and 1990s
• Bob Pellegrini (Armstrong) – NFL 1956–1965
• Anthony Peterson (Washington) – 1994–99 Super Bowl
• Doug Plank (Westmoreland) – NFL safety 1975–1983
• Paul Posluszny (Butler) – Dick Butkus Award winner from Penn State, linebacker for Buffalo Bills
• Scott Radecic (Allegheny) – Penn State and NFL linebacker 1984–95
• Bert Rechichar (Fayette) – 1952–1961 defensive back and kicker
• John Reger – NFL linebacker in the 1950s and 1960s
• Darrelle Revis (Beaver) – cornerback, New York Jets
• Tyrell Sales (Butler) – linebacker 2009–present
• Bryant Salter (Allegheny) – NFL safety in the 1970s
• Joe Schmidt (Allegheny) – linebacker 1953–65, Hall of Fame
• Shawntae Spencer (Allegheny) – NFL cornerback 2000s (decade)
• Russell Stuvaints (Allegheny) – NFL 2000–05
• Tom Tumulty (Allegheny) – NFL 1996–98
• Raymond Ventrone (Allegheny) – safety, Cleveland Browns
• Eric Wicks (Allegheny) – safety, finalist for Bronko Nagurski Award in 2007
• Vic Zucco (Allegheny) – NFL 1957–1960

• George Blanda (Westmoreland) – had extended career as a punter after being a longtime quarterback
• Fred Cox (Washington) – kicker, 1960s and 1970s
• Pat McAfee (Allegheny) – punter, 2009–present
• Bert Rechichar (Fayette) – 1952–61, defensive back and sometime kicker; from 1953 to 1970 held the record for longest field goal
• Don Silvestri (Allegheny) – kicker in the 1990s
• Tom Skladany (Allegheny) – punter 1978–83

• Dave Berry – pro football pioneer
• Kevin Colbert – director of football operations (2 Super Bowls)
• Dale Hamer – NFL referee 1978–2001, 3 Super Bowls
• Shaun Herock – NFL executive
• Bill Nunn – Steelers scout since 1967
• Art Rooney – owner and founder Pittsburgh Steelers Duquesne University
• Dan Rooney – second chairman of the Pittsburgh Steelers, Hall of Famer and current ambassador
• Gene Steratore – NFL official ^[10]
• Tony Steratore – NFL official ^[10]

• Johnny Bulla – won Los Angeles Open
• Scott Dunlap – PGA and Champions Tour
• Bob Friend – PGA and Nationwide Tour
• Jim Furyk (Fayette) – 2003 U.S. Open champion
• Emil Loeffler (Allegheny) – 1920s golfer, course designer
• Rocco Mediate (Westmoreland) – 6-time PGA Tour winner
• Arnold Palmer (Westmoreland) – 95 tournament victories, World Golf Hall of Fame
• Sam Parks, Jr. (Allegheny) – 1935 U.S. Open winner
• Carol Semple (Allegheny) – U.S. Women's Amateur champion
• Jim Simons (Allegheny) – as an amateur nearly won 1971 U.S. Open; first tournament winner using a metal driver
• Stephanie Sparks – LPGA player and commentator
• Steve Wheatcroft – PGA and Nationwide Tour
• Lew Worsham (Allegheny) – 1947 U.S. Open champion

• Pete Babando (Westmoreland) – 1949–67, scored cup-winning goal for Detroit in 1950
• Riley Barber – Miami RedHawks collegiate player
• Matt Clackson (Washington) – AHL 2007–2013
• Christian Hanson (Washington) – Notre Dame of CCHA winger 2005–2009, Leafs 2009
• Ryan Malone (Allegheny) – Penguins, Lightning, Rangers winger 2003–
• J. T. Miller – Rangers
• Gerry O'Flaherty (Allegheny) – Leafs, Canucks, Flames 1971–79
• George Parros (Washington) – Ducks, Canadiens winger 2004–
• Brandon Saad – Blue Jackets winger 2011–
• Henrik Samuelsson (Washington) – Coyotes
• William Thomas (Allegheny) – Coyotes, Penguins, Panthers winger 2005–
• Vincent Trocheck (Allegheny) – Panthers
• R. J. Umberger (Allegheny) – Flyers, Jackets center 2005–
• John Zeiler (Allegheny) – Kings winger 2007–

• Matt Bartkowski (Allegheny) – Canucks
• Bob Beers (Allegheny) – Bruins, Lightning, Oilers, Islanders defenseman 1989–97
• Nate Guenin (Allegheny) – Avalanche 2007–
• Grant Lewis (Allegheny) – Thrashers
• Dylan Reese (Allegheny) – Rangers, Islanders, Penguins 2007–
• Philip Samuelsson (Washington) – Penguins
• Mike Weber (Allegheny) – Sabres defenseman 2007–

• John Gibson (Allegheny) – player for Anaheim Ducks
• Josh Kassel (Westmoreland) – NCAA goalie, first All-American for Army in 30 years

• Stephen Walkom (Allegheny) – referee
• James Wallace Conant (Allegheny) – managed Duquesne Gardens

• Herb Ardinger (Allegheny) – drove in five Indy 500s
• Frank Fox (Allegheny) – auto racer in 1930s
• Chip Ganassi – former driver, now team owner in IndyCar and NASCAR
• Ryan Hemphill (Armstrong) – NASCAR
• Denny Hickey (Fayette) – drove in 1919 Indianapolis 500
• Butch Leitzinger (Allegheny) – 1995–present
• Dick Linder (Allegheny) – 1950s NASCAR driver

• Kurt Angle – 1996 gold medalist in freestyle wrestling, became professional wrestler
• Swintayla Cash – gold medalist in basketball 2004^[11]
• Herb Douglas – long jump bronze medalist at 1948 Summer Olympics; inducted into Pennsylvania Sports Hall of Fame 1992
• Christa Harmotto (Allegheny) – volleyball
• Harry Holiday (Butler) – swimming, set seven world records
• Roger Kingdom – hurdles, gold medalist 1984 and 1988
• Rick Krivda – baseball 2000
• Kristi Leskinen (Fayette) – skiing
• Suzie McConnell-Serio – basketball 1988 and 1992
• Eric Namesnik – swimming
• Bill Schmidt (Washington) – 1972 bronze medalist in javelin
• Johnny Weissmuller – swimming, five gold medals; became actor
• Rod White – archery 2000
• Lauryn Williams – track 2004 and 2008
• Bill Wilmore – weightlifting
• John Woodruff – track
• Daniel Conte pulling hoes

• Nicholas DiOrio – played in 1950 World Cup
• Justin Evans (Washington) – pro player 1999–2009, currently head coach
• Meghan Klingenberg (Allegheny) – player for the Portland Thorns FC and United States women's national soccer team
• Don Malinowski (Allegheny) – U.S. national team player in 1950s
• John Stollmeyer – defender formerly with the US National Soccer Team and US Olympic Team
• A. J. Wood – MLS player
• Marvell Wynne II – defender for MLS side Colorado Rapids

• Bjorn Fratangelo (Allegheny) – French Open boys' champion^[12]
• Bonnie Gadusek – pro tennis player, reached U.S. Open quarterfinals
• Donald Johnson (Allegheny) – top-ranked doubles player
• Gretchen Magers – reached Wimbledon and French Open quarterfinals
• Alison Riske (Allegheny) – WTA player, reached 4th round of U.S. Open

• Eric Angle (Allegheny) – WWE wrestler
• Kurt Angle – 1996 Olympic gold medalist in freestyle; professional wrestler for Total Nonstop Action Wrestling; sportscaster
• Rob Conway – WWE wrestler on RAW brand
• Johnny De Fazio – known as "Jumping" Johnny De Fazio
• Dominic DeNucci – WWWF wrestler and trainer
• Shane Douglas (Beaver) – WCW and WWWF wrestler
• Corey Graves – wrestler, WWE commentator
• Mike Jones – known as Virgil in WWE; worked as Vincent, Shane and Curly Bill in WCW
• Cody Michaels (Allegheny) – former USWA tag team champion, ECW, WSX producer
• John Minton – WWF aka Big John Studd
• Bruno Sammartino – two-time World Wide Wrestling Federation champion
• Mike Scicluna – known as Baron Mikel Scicluna
• John Sullivan – known as Johnny Valiant
• Newton Tattrie – known as Geeto Mongol
• Sylvester Terkay – wrestler with WWE and mixed martial arts (MMA) fighter
• Larry Zbyszko (real name Larry Whistler) – director of authority on Total Nonstop Action Wrestling

• Danny Chew (Allegheny) – cyclist, winner Race Across America (1996, 1999)
• Joseph Kearney (Pittsburgh) – Athletic Administrator
• Joseph M. Papp (Allegheny) – cyclist
• George Smith (Allegheny) – horse racing

• Willard Rockwell (Allegheny) – formed Rockwell Intl.
• Calbraith Perry Rodgers – made the first transcontinental flight
• Helen Richey – first female aviator hired by a commercial airline
• Gustave Whitehead – rival of Wright Brothers
• Doreen Welsh

• James W. Brown – Crucible Steel
• Andrew Carnegie – steel tycoon and philanthropist, founded what became U.S. Steel
• William Donner – steel tycoon, founded Monessen and Donora, daughter married FDR's son in 1932
• William Edenborn – founder of Consolidated Steel and Wire Company, a forerunner of U.S. Steel, emigrated to Pittsburgh from Germany in 1866
• George Washington Gale Ferris Jr. – steel engineer, businessman and inventor of the Ferris wheel
• Henry Clay Frick – steel tycoon, chief operation officer of what became U.S. Steel
• Charles Martin Hall – aluminum producer and founder of Alcoa
• Alfred Hunt (Fayette) – founder of Bethlehem Steel
• B. F. Jones (Allegheny) – Jones & Laughlin Steel
• James H. Laughlin – Jones & Laughlin Steel
• Bernard Lauth (Allegheny) – founder of American Iron Works
• John Leishman – executive at Carnegie Steel
• William Metcalf (Allegheny) – Fort Pitt foundry
• John P. Surma – U.S. Steel
• Thomas Usher – CEO of U.S. Steel and chairman of the board of Marathon Oil
• John Walker (Allegheny) – iron and steel industrialist

• Walter Arnheim – Mobil executive and corporate and non-profit advisor
• Frederick Bausman (Allegheny)
• Samuel Kier – considered the father of the American oil industry
• E. W. Marland – oilman, founded what would become Conoco, also became the governor of Oklahoma
• Andrew W. Mellon – chairman of Mellon Financial, helped to found Westinghouse, Alcoa, Gulf Oil and General Motors, became the longest serving United States Secretary of the Treasury in both years and administrations
• William Mellon – co-founded Gulf Oil
• Thomas Midgley, Jr. (Beaver) – inventor of ethyl gasoline

• Eric F. Buell – Buell Motorcycle Company
• Alexander Cassatt – Pennsylvania Railroad
• Louis Semple Clarke – steamboats
• John E. Connelly – Gateway Clipper Fleet
• Oliver Evans (Allegheny) – pioneer in steam power
• Mike Fink (Allegheny) – river boatman
• Israel Gregg (Fayette) – founded riverboat industry
• Samuel Mason (Washington)
• John McLure (Butler)
• Robert Pitcairn – Pennsylvania Railroad
• Samuel Rea – Pennsylvania Railroad
• Helen Richey (Allegheny) – first female commercial pilot; aviation pioneer
• Henry Miller Shreve – developed and pioneered steamboat and riverboat industries; city of Shreveport, Louisiana named in his honor
• James M. Symes – Pennsylvania RR, attended Sewickley High
• Frederick Way, Jr. (Allegheny) – piloted Delta Queen through the Panama Canal; author; operator of steamboats

• John F. Donahue (Allegheny) – chairman, Federated Investors
• Stanley Druckenmiller (Allegheny) – hedge fund manager
• Thomas Marshall Howe – 19th-century politician
• Trisha Meili (Allegheny) – banker, assault victim
• Richard B. Mellon – banker, philanthropist
• Thomas Mellon – founded Mellon Financial
• Jim Rohr (Allegheny) – CEO of PNC Bank 2000–present
• David Tepper – hedge fund manager
• William Thaw – 19th-century banker

• William Bullock (Allegheny) – printing press innovator
• Bill Campbell (Allegheny) – CEO of Intuit
• Brendan Eich – Mozilla, creator of JavaScript
• John P. Harris (Allegheny) – theater owner
• Vernon Irvin – XM Radio; created "Friends and Families" plan
• Alan W. Livingston (Washington) – Capitol Records CEO
• Andrew Mason (Allegheny) – GroupOn
• Regis McKenna (Allegheny) – high technology marketing guru
• Willard Rockwell (Allegheny) – pioneer of Rockwell Intl.
• Richard Mellon Scaife – Tribune-Review
• Chris Shipley (Westmoreland) – tech analyst
• Rich Skrenta (Allegheny) – computer programmer
• George Westinghouse – electrical industry pioneer
• Mark Whitaker (Allegheny) – CNN Worldwide chief^[13]
• Jamie Zawinski (Allegheny) – hacker
• Donnie Gray (Lawrence) – computer guy

• Peter Chartier (Chartiers Town and Tarentum) – fur trader 1734-43
• David L. Clark (Allegheny)
• Joseph A. Hardy III (Fayette) – 84 Lumber
• H. J. Heinz II – CEO of H.J. Heinz Co.
• Henry J. Heinz – founder of H. J. Heinz Company
• Billy Mays – TV pitchman
• Frank E. Resnik (Westmoreland) – CEO of Phillip Morris 1984–91
• James Sinegal – Costco
• Burton Tansky (Allegheny) – Neiman Marcus 2001–10
• Patricia A. Woertz (Allegheny) – ADM^[14]
• William Ziegler (Beaver) – co-founder of Royal Baking Company

• William D. Boyce – founder of Boy Scouts of America
• Dr. Herbert Boyer – co-founder of Genentech
• John Baptiste Ford – PPG Industries
• Ed Grier – Disneyland
• Joseph A. Hardy III – 84 Lumber
• George E. Merrick (Allegheny) – created first planned communities
• Dan Radakovich (Beaver) – athletic director
• Robert J. Stevens (Allegheny) – CEO of Lockheed Martin
• Bob Stupak – Vegas Stratosphere
• Dewey Tomko (Allegheny) – poker player

• Frank Fitzsimmons (Westmoreland) – Teamsters president; 1967–81 confidant of Jimmy Hoffa
• Edwin D. Hill (Beaver) – president of IBEW 2001–
• David J. McDonald (Allegheny) – president of steelworkers union
• Fannie Sellins – union organizer
• Richard Trumka (Greene) – president of the AFL-CIO 2009–present, UMW (1982–95)
• Joseph Yablonski – UMW
• Joseph "Chip" Yablonski – UMW attorney
• Kenneth Yablonski – attorney

• Benjamin W. Arnett (Fayette) – theologian, first African-American who won a majority white district (assemblyman for Ohio)
• Robert Baird (Fayette) – clergyman and author
• Joseph Baldwin (Lawrence) – father of the "Normal School"
• Cardinal Daniel DiNardo – archbishop of Galveston-Houston
• Thomas Dolinay (Fayette) – archbishop
• Hutton Gibson (Westmoreland) – father of actor Mel Gibson^[15]
• Kersey Graves (Fayette) – atheist and philosopher; mentioned in the film The DaVinci Code
• Charles Hartshorne (Armstrong)
• Charles William Kerr (Butler) – leader in race relations, quelled the Tulsa Race Riots
• Joseph R. Lamonde (Allegheny)
• Countess Leon (Beaver) – Rappitte leader
• Cardinal Adam Maida (Westmoreland) – Emeritus Archbishop of Detroit
• Bernhard Müller (Beaver)
• Madalyn Murray O'Hair – founder of American Atheists
• William Passavant (Butler)
• Victor J. Pospishil (Armstrong)
• Charles D. Provan (Washington)
• George Rapp – founder of the religious sect Harmonists
• Charles Owen Rice (Allegheny)
• Charles Taze Russell – founder of Watch Tower Bible & Tract Society
• R. C. Sproul – theologian
• Thomas J. Tobin (Allegheny) – auxiliary bishop of Pittsburgh, bishop of Youngstown OH, and current Bishop of Providence, Rhode Island
• Cardinal Donald Wuerl – eleventh bishop of the Roman Catholic Diocese of Pittsburgh, current Archbishop of Washington
• David Zubik – twelfth and current bishop of the Roman Catholic Diocese of Pittsburgh

• Edward Goodrich Acheson (Washington) – chemist
• Ross Allen – herpetologist
• Sara Alpern – women's historian at Texas A&M University
• David Alter (Westmoreland) – leading inventor of spectrum analysis and early telegraphs and telephones
• Christian B. Anfinsen (Westmoreland) – Nobel Prize winner
• Frederick S. Billig – scramjet pioneer
• Andrew H. Bobeck (Fayette) – Bell Labs scientist, invented bubble memory
• Dr. Herbert Boyer (Westmoreland) – co-founder of Genentech
• Rachel Carson – author, marine biologist, nature writer, and environmentalist
• Yuan Chang – virologist, co-discoverer of causes of several viral cancers, including Kaposi's sarcoma
• Norman Christ (Allegheny) – physicist
• Ralph J. Cicerone (Lawrence) – National Academy of Sciences President
• Robert L. Coble (Fayette)
• Childs Frick (Allegheny)
• George Otto Gey (Allegheny) – scientist who propagated the HeLa cell line
• Richard Hartshorne (Armstrong) – geographer
• M. Stephen Heilman (Allegheny)
• John Holdren (Allegheny)
• William Jacob Holland – entomologist and chancellor of the Western University of Pennsylvania
• Stephanie Kwolek (Westmoreland) – inventor of Kevlar
• Dorothy Molter (Westmoreland) – naturalist
• Helen Morrison (Westmoreland) – criminologist
• George C. Nichopoulos (Allegheny) – Elvis' personal physician
• H. Winnett Orr (Westmorland) – leading research doctor, invented and popularized the plaster cast method
• Randy Pausch, founder of Alice, and man behind the Last Lecture
• Judith Resnik – biomedical engineer and astronaut who died in the destruction of the Space Shuttle Challenger; second American woman and second Jew in space
• John Roebling (Butler) – civil engineer, a pioneer in the construction of suspension bridges^[16]
• Washington Roebling (Butler) – civil engineer best known for his work on the Brooklyn Bridge
• David Roselle (Westmoreland) – mathematician; President of Univ. of Kentucky; President of Univ. of Delaware
• Jonas Salk – physician, inventor of first polio vaccine
• Oliver B. Shallenberger (Beaver)
• Harriet Shetler (Armstrong) – founder of the National Alliance for Mental Illness
• Alex Shigo – arboriculturist and horticulturist
• Clifford Shull (Allegheny) – Nobel Prize winner
• Herbert A. Simon – Carnegie Mellon University professor; winner of Nobel Prize for Economics
• Herbert Spiegel (Allegheny) – popularized the use of hypnosis therapy
• Thomas Starzl – pioneering transplant surgeon in liver and multiorgan transplantation
• Jesse Steinfeld – United States Surgeon General under Nixon
• Otto Stern – German-American physicist and Nobel laureate, known for his studies of molecular beams; Carnegie Institute of Technology professor (now Carnegie Mellon University)
• James L. Swauger (Westmoreland)
• Nicholas E. Wagman (Allegheny)
• Sandra Welner (1958–2001) – physician, advocate for disabled women's healthcare
• Jerome Wolken (1917–1999) – biophysicist^[17]
• Jamie Zawinski (Allegheny)
• Jonathan Zittrain (Allegheny) – professor of Internet law and computer science at Harvard
• Vladimir Zworykin – engineer and inventor, developed an early form of television; the IEEE presents a Vladimir Zworykin Award for outstanding contributions to development of television technology

• John Armstrong, Sr. – Major General during Revolutionary War
• Ebenezer Denny (Allegheny) – 10th Adjutant General of the U.S. Army
• Edward Hand (Allegheny) – 8th Adjutant General of the U.S. Army
• Archibald Lochry (Westmoreland) – general in French and Indian Wars
• John Neville – General, suppressed the Whiskey Rebellion
• Arthur St. Clair – Major General during Revolutionary War

• Absalom Baird (Washington)
• John M. Corse (Allegheny)
• Richard Coulter (Allegheny)
• Richard C. Drum (Westmoreland)
• Benjamin Grierson (Allegheny) – Civil War and Buffalo Soldier
• Alexander Hays – Brigadier General*, repulsed Pickett's Charge at Gettysburg
• Francis J. Herron (Allegheny)
• Daniel Leasure (Westmoreland)
• Alexander Murray (Allegheny) – Admiral
• James Scott Negley (Allegheny) – Major General Civil War hero of Murfreesboro
• Robert Orr, Jr. (Westmoreland) – General War of 1812
• Thomas A. Rowley (1808–92) – Brigadier-general; Gettysburg; Civil War
• Jacob B. Sweitzer (Fayette) – General* Civil War, led major offensives at Gettysburg
• Martin Varner (Fayette) – one of the "Original 300" Texas settlers; leader of Texas Revolution, battle of San Jacinto
• Samuel Baldwin Marks Young (Allegheny)

• George C. Axtell (Beaver) – General*** United States Marine Corps
• Donald M. Carpenter (Allegheny)
• Duane H. Cassidy (Allegheny)
• Richard Coulter, Jr. (Westmoreland) – General, Spanish–American War and World War I
• Ivor Parry Evans (Beaver)
• Joseph R. Lamonde
• Manus MacCloskey – Brigadier General
• George Marshall – General of the Army *****
• Jack G. Merrell (Westmoreland)
• Admiral Robert Peary – first person to reach the North Pole
• Joseph Henry Pendleton (Beaver) – General** Camp Pendleton named in his honor
• Matthew Ridgway – General ***
• Paul K. Van Riper (Fayette) – General*** Marine Corps
• Carl E. Vuono (Washington) – General**** Chief of Staff Army 1987–91
• Samuel Baldwin Marks Young (Allegheny) – first Chief of Staff of the Army

• Jonathan Greenert (Butler)^[18]
• Michael Hayden (Allegheny) – USAF ****, Director of NSA, CIA
• John F. Sattler (Allegheny)
• Dennis E. Wisnosky (Washington) – CTO of Pentagon
• Rob Wyda (Allegheny) – leading JAG officer, Bagram and Guantanamo military commission

• Charles Bishop
• Robert Semple

• Absalom Baird (Washington)
• Amzi D. Harmon (Allegheny)^[19]
• Charles Higby (Allegheny)
• Alexander Kelly (Allegheny)
• Alfred L. Pearson (Allegheny) – Medal of Honor
• James Schoonmaker (Allegheny)

• Arthur V. Ely (Allegheny)
• Leonard A. Funk, Jr. (Allegheny)
• Raymond Harvey (Armstrong)
• Charles E. Kelly (Allegheny)
• Donald R. Lobaugh (Armstrong)
• Archibald Mathies (Washington)
• Mitchell Paige (Washington)
• John J. Pinder, Jr. (Allegheny) – Normandy
• William A. Shomo (Westmoreland)
• Alfred L. Wilson (Fayette)

• Reginald B. Desiderio (Allegheny)
• Anthony Herbert (Allegheny)
• John D. Kelly (Allegheny)

• Ralph Ellis Dias
• Michael Estocin
• John Gertsch
• James A. Graham
• Anthony Herbert (Westmoreland)
• Walter Joseph Marm, Jr. (Washington)
• William D. Morgan
• Melvin E. Newlin
• Michael Novosel
• William Port
• William Prom
• Leslie H. Sabo, Jr.
• Carl E. Vuono (Washington)
• David F. Winder

• Henry Clay Drexler (Allegheny) – 1924
• William E. Snyder (Armstrong) – Medal of Honor 1910

• Jay Apt – astronaut and professor
• Mike Fincke – Colonel, United States Air Force
• Terry Hart – Lieutenant Colonel, United States Air Force
• James Irwin – lunar module pilot of Apollo 15
• Judith A. Resnick (Allegheny) – killed in Challenger explosion
• Joseph Albert Walker (Washington) – NASA test pilot

• Adrian Cronauer – soldier, radio personality, subject of Good Morning, Vietnam
• Charles Graner (Allegheny) – U.S. Army reservist convicted of prisoner abuse in connection with 2003–2004 Abu Ghraib prisoner abuse scandal
• Philo McGiffen (Washington) – 19th-century naval officer
• James Veneris (Westmoreland) – World War II and Korea vet who defected to China

• Christian H. Buhl (Butler) – Mayor of Detroit
• Frederick Buhl (Butler) – Mayor of Detroit
• James Clarke (Westmoreland) – Governor of Iowa
• Tom Corbett (Allegheny) – Governor of Pennsylvania
• William Corbett (Allegheny) – Governor of Guam
• Bob Cranmer – Allegheny County Commissioner
• Mitch Daniels (Washington) – Indiana governor 2005–2013
• Bob Filner (Allegheny) – San Diego mayor
• John F. Forward, Sr. (Allegheny) – 12th mayor of San Diego
• John F. Forward, Jr. 21st mayor of San Diego
• Alexander Fulton (Washington) – founder of Alexandria, Louisiana
• John W. Geary (Westmoreland) – Governor of Pennsylvania and Kansas, 1st San Francisco mayor
• Barbara Hafer – first female Allegheny County Commissioner
• L. B. Hanna (Beaver) – Governor of North Dakota
• William Hendricks (Westmoreland) – Governor of Indiana; moved capital to Indianapolis; uncle of another governor of the state
• John Herriott (Allegheny) – Iowa Lt. Governor 1902–07.
• William F. Johnston (Westmoreland) – Pennsylvania Governor 1848–1852
• John Kasich – Ohio Representative (1983–2001), Governor of Ohio since 2011, and 2000/2016 Republican candidate for president
• John Henry Kinkead (Fayette) – Governor of Nevada, 1st governor of Alaska
• Ernest Kline (Westmoreland) – Lt. Governor of Pennsylvania 1971–79
• William Carr Lane (Fayette) – first mayor of St. Louis; third governor of New Mexico
• Gary Leitzell (Allegheny) – Mayor of Dayton
• E. W. Marland (Allegheny) – Governor of Oklahoma
• John Martin (Fayette) – Governor of Kansas, founder of the abolitionist movement
• Elliot S.N. Morgan (Allegheny) – Wyoming governor
• Janet Napolitano (Allegheny) – Arizona governor
• Joshua G. Newbold (Fayette) – Iowa governor
• Tom Ridge (Allegheny) – Governor 1995–2001; first Secretary of Homeland Security
• John F. Seymour (Allegheny) – Mayor of Anaheim 1978–82
• John K. Tener (Allegheny) – Governor, former MLB pitcher
• Dick Thornburgh (Allegheny) – Governor 1979–87; U.S. Attorney General 1987–91
• Tom Vilsack (Allegheny) – Iowa Governor, 1999–2007; Agriculture Secretary, 2009–

• Eugene Atkinson (Beaver) – congressman
• Michael Bilirakis (Allegheny) – Florida congressman
• James G. Blaine (Washington) – Senator from Maine, twice runner-up for president
• William A. Clark (Fayette) – Montana Senator, founded Clark County, Nevada and Clarksville, Arizona
• Edgar Cowan (Westmoreland) – Senator 1861–67
• John Dalzell (Allegheny) – Congressman 1887–1913; Chairman of the Ways and Means committee 1898–1913
• Geoff Davis – Kentucky Congressman
• John Littleton Dawson (Fayette) – Congressman 1851–67; offered governorship of Kansas; namesake of Dawson County, Nebraska
• Harmar Denny – Congressman 1825–37
• Mike Doyle – Congressman
• Tom Feeney Florida Congressman
• Homer S. Ferguson (Westmoreland) – Michigan Senator 1943–55, Ambassador to the Philippines
• Bob Filner (Allegheny) – California Congressman 1993–2012
• Joseph F. Guffey (Westmoreland) -Senator, 1930s and 1940s
• Orrin Hatch – Utah Senator, 1977–
• John Heinz – Congressman 71–77, Senator 1977–91
• Thomas Marshall Howe – Congressman 1851–55
• John Kasich – Ohio Congressman 1983–01, governor 2011–
• Philander C. Knox – Senator 1901–04, 1917–21, United States Attorney General from 1901–04, Sec. of State from 1909–13
• Robert McKnight – Congressman 1859–63
• George T. Oliver – Senator 1909–17
• Rand Paul – Kentucky Senator 2011–present, Tea Party leader
• Ron Paul – Texas Congressman, presidential candidate
• David A. Reed (Allegheny) – U.S. Senator
• Rick Santorum – Congressman 1991–95, Senator 1995–2007
• Claudine Schneider – Congresswoman Rhode Island 1981–91
• John F. Seymour (Allegheny) – U.S. Senator from California
• John Smilie (Fayette) – Congressman 1793–1812, leader of Anti-Slavery Caucus, founder of abolition
• Amos Townsend (Fayette) – Ohio Congressman 1877–83
• Bill Young (Allegheny) – Florida Congressman 1970–present
• Morgan Ringland Wise (Allegheny)
• John Woods (Fayette) – U.S. Congressman
• Frederick Nicholas Zihlman (Allegheny) – Congressman 1917–31

• Marcus Acheson (Washington) – Federal 1880–91, Appeals 1891–1906
• Ruggero J. Aldisert (Allegheny) – Chief Judge Appeals Court US 3rd Circuit
• Anne X. Alpern (Allegheny)
• Donetta Ambrose – Federal 1993–, Chief Judge 2002–
• Max Baer (Allegheny) – Pennsylvania Supreme Court 2003–
• William Bassler – Federal 1991–06 for N.J. circuit
• Derrick Bell – law professor
• Robert Bork – Supreme Court nominee, and acting AG
• Joseph Buffington (Armstrong) – Federal 1892–47, Appeals 1906–47
• Jeremiah Burrell (Westmoreland) – Federal 1847–56
• Ralph Cappy (Allegheny) – Chief Justice Pennsylvania Supreme Court 2003–08
• Robert J. Cindrich (Washington) – Federal 1994–2004
• George Dallas (Allegheny) – Fed. Court of Appeals 1892–1909
• Edward Dumbauld (Fayette) – Federal 1961–76
• Nathaniel Ewing (Fayette) – Federal 1906–08
• Michael Fisher (Allegheny) – Federal Appeals 2003–
• Albert Gordon – advocate for gay rights^[21]
• Ken Gormley (Allegheny)
• Philip Heymann (Allegheny) served in Carter and Clinton administrations
• William G. Hundley – Justice Department prosecutor and criminal defense attorney for high-profile clients, born in Pittsburgh in 1925^[22]
• Linda Kelly (Allegheny) Pennsylvania Attorney General
• Gary Lancaster (Fayette) Federal 1987–present
• Rolf Larsen (Allegheny) State Supreme Court Justice
• Donald J. Lee (Allegheny) Federal 1989–2000
• Timothy K. Lewis (Allegheny) Federal 1991–92, Appeals 1992–99
• Walter H. Lowrie (Armstrong) State Supreme Court Chief Justice
• Carol Los Mansmann (Allegheny) – Federal 1982–85, Appeals 1985–2002
• Rabe Ferguson Marsh, Jr. (Westmoreland) – Federal 1950–77
• Wilson McCandless (Allegheny) – U.S. Judge
• Barron McCune (Westmoreland) – Federal 1970–95, Pittsburgh drug trials
• John Wilson McIlvaine (Washington) – Federal 1955–63
• William McKennan (Washington) – U.S. Judge
• Trisha Meili (Allegheny)
• Joan Melvin (Allegheny) – Pennsylvania Supreme Court 2009–
• John Lester Miller (Allegheny) – 1954–71
• Michael Angelo Musmanno (Allegheny) – PA Supreme Court and Nuremberg tribunal
• Ethelbert Oliphant (Fayette) – founding justice Washington Supreme Court
• Charles Prentiss Orr (Allegheny) – 1909–22
• Deborah Palfrey (Westmoreland) – law student who became the D.C. Madam
• Norman Ramsey – Federal 1980–92
• James Reed – Federal Judge and U.S. senator
• Louis Rosenberg (Beaver) – Federal 1962–76
• Ralph Francis Scalera (Beaver) – Federal 1971–76
• Arthur Schwab – U.S. Judge 2002–present
• George Shiras – U.S. Supreme Court
• Daniel John Snyder, Jr. (Westmoreland) – Federal 1973–80
• Herbert Peter Sorg (Elk) – Federal 1955–76
• William Alvah Stewart (Allegheny) – Federal 1951–53
• Hubert Irving Teitelbaum (Allegheny) – 1970–1985
• W. H. Seward Thomson (Beaver) Federal – 1914–28
• Gerald Tjoflat – Appeals 1975–present
• Debra Todd – Pennsylvania Supreme Court 2007–
• Joseph F. Weis, Jr. (Allegheny) – Federal 1970–73, Appeals 1973–88
• Veronica Wicker (Westmoreland) – Federal 1977–94 in New Orleans
• James Scott Young (Allegheny) – Federal 1908–14
• Donald Emil Ziegler (Allegheny) – Federal 1978–2003

• Gust Avrakotos (Beaver) – CIA leader and pointman for Afghanistan missions in 1980s, featured in Charlie Wilson's War
• Victoria "Torie" Clarke – Assistant Secretary of Defense for Public Affairs under George W. Bush
• Michael Hayden – CIA director 2006–09
• John Kiriakou (Lawrence) – CIA analyst
• John E. McLaughlin (Allegheny) – CIA Deputy Director and Acting Director 2004
• William Perry (Westmoreland) – U.S. Secretary of Defense 1994–1997

• James G. Blaine – Secretary of State, twice runner-up for president
• James J. Davis – Secretary of Labor under presidents Harding, Coolidge, and Hoover
• Walter Forward – United States Secretary of the Treasury under John Tyler, 1841–1843
• Albert Gallatin – Treasury Secretary
• John Holdren – OSTP Director 2009–
• Andrew Mellon – longest-serving United States Treasury Secretary in US history
• Paul O'Neill – 72nd United States Secretary of the Treasury

• Edward P. Brynn (Allegheny) – Burkina Faso and Ghana
• Homer S. Ferguson – Philippines
• Walter Forward – Denmark
• George W. Guthrie – Japan
• William W. Irwin – Denmark
• Andrew Mellon – Great Britain 1932–33
• Alexander Pollock Moore – Spain and Peru
• Ronald D. Palmer – 1976 to 1989
• Dan Rooney – Ireland 2009–present
• Edith S. Sampson – first African-American in the U.N. (1950–53) and NATO (1961–62)
• Adolph W. Schmidt (Allegheny) – Canada 1969–74
• Phillips Talbot – Greece
• Judge Wilkins (Allegheny) – Russia 1834–35
• Cyrus Woods (Westmoreland) – ambassador 1910s–30s

• William Campbell (Coraopolis) – member of the California State Assembly and California State Senate
• David Dank (Allegheny) – member of the Oklahoma House of Representatives since 2007
• John R. Jones (Allegheny) – member of the Wisconsin State Assembly
• Andrew P. Kealy (Allegheny) – member of the Wisconsin State Assembly
• Alexander McDonald Thomson (Allegheny) – Speaker of the Wisconsin State Assembly
• Peter J. Tropman (Allegheny) – member of the Wisconsin State Assembly

• John Brabender (Allegheny)
• Murray Chotiner (Allegheny)
• Frank Cowan (Westmoreland) – Secretary for President Johnson; donated Mt. Odin Park to Greensburg
• Patrick R. Donahoe (Allegheny)
• Tony Fratto (Allegheny) – Deputy Press Secretary 2006–09
• Elsie Hillman – former Republican National Committeewoman from Pennsylvania
• Jo Ann Krukar (Armstrong) – Veterans Administration officer 1989–1993; wife of Senator James Webb
• Bob Shrum (Fayette) – political advisor and consultant on national campaigns since the 1970s
• Eleanor Smeal (Allegheny) – NOW President 1978–1987

• Vic Cianca – Pittsburgh traffic cop made famous by Johnny Carson, Candid Camera and Flashdance
• Thomas Delahanty – police officer who took a bullet in President Ronald Reagan's 1981 assassination attempt; declared a hero and awarded a medal for bravery

• Bowman Foster Ashe (Westmoreland) – founding president of the University of Miami
• William C. Byham (Allegheny)
• John Taylor Gatto (Washington)

• Queen Alliquippa (Beaver)
• Princess Lida of Thurn and Taxis (Fayette)