List of Total Drama: Revenge of the Island episodes

Back at Camp Wawanakwa (the original location of the first season of Total Drama), the area has been used as a bio-hazardous waste dump, causing all of the island's environment and creatures to become radioactive. Thirteen new contestants are introduced: Anne Maria, B, Brick, Cameron, Dakota, Dawn, Jo, Lightning, Mike, Sam, Scott, Staci, and Zoey. They are divided into two teams: the Toxic Rats and the Mutant Maggots. Near the end of the first challenge, Owen asks Chris if the original contestants are going to compete again, which Chris denies before blowing Owen back off the island.

As the competition narrows to 12, the contestants face a "Truth or Dare" challenge, which forces the contestants to either embarrass themselves by saying the truth, or have their entire team be plunged into shark-infested waters. During the challenge, Sam reveals he farted on his only date, Brick reveals he wet his pants on his first and last day of school one year, and B's reveals his first name is Beverly. After a dip in the water in the midst of the challenge, Scott inadvertently begins a rivalry with Fang (a large, mutated shark with two legs) when, after he escapes certain consumption, he knocks out one of the shark's teeth and chooses to keep it. The contestants begin to bicker over the challenge, until Chris decides to cancel it and move them into an even more dangerous one. Throughout the episode, Mike continues his growing relationship with Zoey, while Sam starts a relationship with Dakota.

In the cafeteria, Mike tries to explain his personality problem by telling everyone that he is role-playing, but admits his disorder at the confessional. The contestants are taken to the first challenge: to climb up a mountain to the top with their bare hands and feet, or by using stuff from a junk pile that is owned by a giant mutated cockroach. While climbing the mountain, they must avoid the stuff that Chef throws at them. The Toxic Rats manage to get to the top of the mountain first by slingshotting themselves on a sofa to the top, winning the first challenge and earning them an advantage in the second challenge: a "Capture the Flag" challenge where each of the teams owns an ice castle in a snowy area, and must destroy each other's castle, either by melting or by snowballs, in order to capture the other team's flag.

The 10 remaining campers compete in a spooky challenge in which they are taken to the forest and must navigate their way to a cemetery, dig up and open a coffin, grab a flashlight from inside the coffin, then find their way around the forest to the finish line. Throughout the challenge, they encounter several mutated animals. A giant pink spider attacks and captures all of the contestants except Mike, Cameron, and Anne Maria. Scott's rivalry with his archnemesis Fang the shark continues when he's ambushed by him in the cemetery.

Mike's Vito personality continues to attract Anne Maria and causes her and Mike to get together, without Mike remembering Zoey. When set off to fight the giant spider, Zoey sees Mike and Anne Maria kissing and begins to get jealous. Cameron and Svetlana rescue everyone from the giant spider. However, the Rats win the challenge and the Maggots lose for the first time. When Cameron defeats the spider, it is revealed that the spider has been Izzy inside a giant spider costume.

Both teams face off in a fashion contest by finding models (who are actually the mutated creatures) on the island. They save Lindsay after she is kidnapped by Sasquatchanakwa after Sam gets the wrong idea about stripes from Dakota. Sasquatchanakwa becomes furious and Dakota says she meant vertical stripes because horizontal stripes make anything or anyone look fat. During the challenge, Scott's rivalry with Fang heats up after he tricks him into falling into one of his own traps, and he tries to sow some seeds to get Zoey under his thumb in the future.

The Maggots' cabin is destroyed when the teams merge. The contestants must search the kitchen for keys to the go-karts. They use the go-karts to go to three different locations around the island and spray-paint their symbol on each location. Zoey's symbol is a heart, Scott's is an X, Mike's is a check, Cameron's is a picture of Chris giving him the money, Jo puts a circle with a line through it on top of Cameron's symbol, then Cameron switches to the pi symbol, and Lightning's symbol is a lightning bolt. Chef tricks the contestants into going to a fourth location, the Chris Monument (called Mount Chrismore).

Jo and Lightning are briefly detained by Chef, and Fang is ordered to guard them. Jo escapes by using Lightning as a distraction for Fang, but Lightning gets away himself by offering up Scott to Fang. Scott used Mike's multiple personality disorder to his advantage by threatening to tell Zoey about it if Mike doesn't do what he says. However, Zoey discovers Mike's condition through another source.

Mike overcomes his personalities, and he and Zoey become a couple. Scott wins invincibility and gets to decide who should leave. Mike is voted off by Scott, and he gives Zoey a pendant to remember him by. They almost kiss until Mike is catapulted. Duncan, a former contestant, makes brief cameos throughout the episode.

The remaining five contestants must now fly through rings of fire by using a specific flying object provided by Chris, but first they must go to the waste dump to find the pieces in order build to their flying object. Jo has to build a flying balloon, Lightning must build a helicopter, Zoey must build a plane, Cameron gets to build a rocket ship and Scott must build a bird. To test the rings of fire to determine if they are safe to fly through, Chris uses Heather as a test dummy to see if she survives the flight. Heather uses a jet pack and she survives. While the contestants are building their flying objects, Zoey is mad that Scott eliminated Mike, so she steals Scott's parts to build her plane, causing Scott to get nothing except a pair of wings he got from birds.

At the challenge, the five are ready to fly their objects through the rings of fire, but Heather gets mad and steals the million dollar case from Chris and takes off on a blimp. The challenge is now to chase the blimp and capture Heather to retrieve the money. Everyone is chasing the blimp and, during flight, Zoey flies on radioactive flying goats that breathe fire, emabling her to take her revenge on Scott by shooting fire at him. Scott has to deal with Fang trying to eat him, both on land and in the air. Lightning gets on the blimp, and retrieves the money case from Heather.

Chris is injured by one of Scott's shark traps and crashes into the restrooms. Chef temporary becomes the host and makes the contestants do a cooking challenge. Cameron makes some quiche pie with radioactive mushrooms, Scott makes a more toxic quiche, Zoey made a living salad, and Lightning cooks a mutated maggot. They are supposed to feed their meals to classic competitor DJ, but he runs away and they are forced to eat what they have cooked. Scott switches his quiche with Cameron, and ends up winning the challenge, with the others puking.

Chef then puts them through a hunting challenge with the contestants as the prey. They are to make it to a flagpole before Chef catches them with a spaghetti bazooka. After Chef injures Zoey and breaks her pendant, she becomes bent on revenge against Scott and Chef. Scott makes it to the flagpole first and almost wins the challenge, but suddenly, Fang appears, chases him, and reveals that he's only been chasing Scott because he took his tooth, which Scott refuses to return to him. Fang then is caught by one of Zoey's traps, while another trap hits Scott, putting him in a full-body cast.

Zoey and Cameron agree to team up against Lightning to eliminate him before the final two. Cameron is interested in doing so because he knows Lightning is targeting him for stealing invincibility from him. Chris sends the final three campers into the enchanted forest to retrieve a flower from a Venus flytrap named Larry. Inside the forest, the campers encounter mutated animals, including Ezekiel. Throughout the challenge, Zoey starts to be rude to Cameron, while Lightning gets lost. Cameron then realizes that Zoey is changing, but Zoey gives up winning the challenge to save Cameron from dying, and Lightning wins the challenge.

Lightning and Cameron, the final two contestants, are told to vent all of their feelings in the confessional. They both watch video messages on a television from their relatives at home. Lightning's father bets his championship rings that Lightning can win. They arrive at a massive arena where Chris, Chef, two interns, and the 11 previously-eliminated contestants are watching them from the stands. A pile of junk is dropped into the middle of the arena, and the two finalists must find a way to use some of the junk as either armor or weapons for a duel. Lightning creates a rather crude set of armor with ankle plates, a chest plate, a pan as his helmet, and a plastic mannequin's leg with nails sticking out of the top. Cameron creates a mechanical suitcase that turns him into Iron Man.

The battle begins, and the two battle for so long with no clear winner that Chris decides to make it interesting and drops every mutated creature from the island into the arena. The creatures (including Ezekiel) start attacking everyone. Cameron tries to save the other contestants from the monsters, while Lightning keeps attacking Cameron only. Eventually, one of Cameron's iron suit's abilities causes many of the barrels of toxic waste to magnetize to Lightning's body armor, giving Lightning white hair and causing him to get tired and black out. Cameron gets tired, too, and falls on top of Lightning, causing Cameron win the final challenge.

Chris crowns Cameron the winner of Total Drama: Revenge of the Island and the new recipient of the million dollars. As Chef and the 13 contestants sail away on a boat, Chris attempts to detonate a bomb placed on the underside of the boat, but the bomb goes off on the dock directly beneath Chris, because Chef moved the bomb. The Royal Canadian Mounted Police descends on the island, putting the island under government protection. Chris is ordered to be quarantined, while Chef and the rest of the cast flee and cheer.

Alternate Ending: In the United States, Cameron's suit runs out of power and he collapses to the ground. Afterwards, Lightning is shocked by a lightning bolt, making his hair turn white while he topples over Cameron, pinning Cameron down for three seconds, thereby making Lightning the winner.