Lasalocid

Lasalocid
Clinical data

AHFS/Drugs.com	International Drug Names
ATCvet code	QP51AH02 (WHO)
Identifiers
IUPAC name 6-[(3R,4S,5S,7R)-7-[(2S,3S,5S)-5-ethyl-5-[(2R,5R,6S)-
CAS Number	25999-31-9^N
PubChem (CID)	5360807
ChemSpider	4514598^Y
UNII	W7V2ZZ2FWB^Y
KEGG	D04671^Y
ChEMBL	CHEMBL145347^Y
ECHA InfoCard	100.043.077
Chemical and physical data
Formula	C₃₄H₅₄O₈
Molar mass	590.79 g/mol
3D model (Jmol)	Interactive image
SMILES O=C(O)c1c(O)c(ccc1CC[C@@H](C)[C@H](O)[C@@H](C(=O)[C@@H]([C@H]3O[C@@]([C@@H]2O[C@H]([C@](O)(CC2)CC)C)(CC)C[C@@H]3C)CC)C)C
InChI InChI=1S/C34H54O8/c1-9-25(31-21(6)18-34(11-3,42-31)26-16-17-33(40,10-2)23(8)41-26)30(37)22(7)28(35)19(4)12-14-24-15-13-20(5)29(36)27(24)32(38)39/h13,15,19,21-23,25-26,28,31,35-36,40H,9-12,14,16-18H2,1-8H3,(H,38,39)/t19-,21+,22+,23+,25+,26-,28+,31+,33-,34+/m1/s1^Y Key:BBMULGJBVDDDNI-OWKLGTHSSA-N^Y
^NY (what is this?) (verify)

Lasalocid is an antibacterial agent and a coccidiostat, which is produced by strains of Streptomyces lasaliensis. It is the drug in the feed additives called Bovatec and Avatec.^[1]

Lasalocid is able to make neutral complexes with monovalent and divalent cations and transport them through apolar phase (including lipid bilayer membranes). It can also transport big organic cations like dopamine.

Horses and dogs^[2] are very susceptible to the toxic effects of lasalocid, and it should never be administered to non-target species.

References

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