LY-255582
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| Names | |
|---|---|
| IUPAC name
3-{(3R,4R)-1-[(3S)-3-Cyclohexyl-3-hydroxypropyl]-3,4-dimethyl-4-piperidinyl}phenol | |
| Identifiers | |
| 3D model (Jmol) | Interactive image |
| ChemSpider | 8081850 |
| PubChem | 9906198 |
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| Properties | |
| C22H35NO2 | |
| Molar mass | 345.53 g·mol−1 |
| Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
| Infobox references | |
LY-255582 is a phenylpiperidine non-selective opioid antagonist. It has been shown to reduce ethanol consumption in experiments carried out on rats.[1] It has also been shown to reduce food and water consumption in rats.[2]
References
- ↑ Dhaher R, et al. (Feb 2012). "Effects of naltrexone and LY255582 on ethanol maintenance, seeking, and relapse responding by alcohol-preferring (P) rats.". Alcohol. 46 (1): 17–27. doi:10.1016/j.alcohol.2011.08.011.
- ↑ Shaw WN, et al. (Jun 1991). "The effect of the opioid antagonist LY255582 on body weight of the obese Zucker rat.". Int J Obes. 15 (6): 387–95. PMID 1653188.
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