Ameriks studied at Yale University, A.B., summa cum laude (1969), Ph.D. (1973), where he wrote his thesis under the direction of Karsten Harries. He is regarded as one of the foremost scholars of the philosophy of Immanuel Kant and has written widely in the history of continental and modern philosophy. Ameriks co-edits the series Cambridge Texts in the History of Philosophy. He was elected a Fellow of the American Academy of Arts and Sciences in 2009.
- Kant's Theory of Mind: An Analysis of the Paralogisms of Pure Reason (Oxford: Clarendon Press, 1982; expanded ed., 2000)
- Kant and the Fate of Autonomy: Problems in the Appropriation of the Critical Philosophy (Cambridge: Cambridge Univ. Press, 2000)
- Interpreting Kant’s Critiques (Oxford: Clarendon Press, 2003)
- Kant and the Historical Turn: Philosophy as Critical Interpretation (Oxford: Clarendon Press, 2006)
- Kant's Elliptical Path (Oxford: Clarendon Press, 2012)
- "Book of Members, 1780-2010: Chapter A" (PDF). American Academy of Arts and Sciences. Retrieved 17 April 2011.