Isofuran

Isofurans are nonclassic eicosanoids formed nonenzymatically by free radical mediated peroxidation of arachidonic acid. The isofurans are similar to the isoprostanes and are formed under similar conditions, but contain a substituted tetrahydrofuran ring. The concentration of oxygen affects this process; at elevated oxygen concentrations, the formation of isofurans is favored whereas the formation of isoprostanes is disfavored.[1]

References

  1. ↑ Roberts, LJ 2nd and Fessel, JP (Mar 2004). "The biochemistry of the isoprostane, neuroprostane, and isofuran pathways of lipid peroxidation.". Chem Phys Lipids. 128 (1–2): 173–86. doi:10.1016/j.chemphyslip.2003.09.016. PMID 15037162.


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