INTS1
| INTS1 | ||||||
|---|---|---|---|---|---|---|
| Identifiers | ||||||
| Aliases | INTS1, INT1, NET28, integrator complex subunit 1 | |||||
| External IDs | MGI: 1915760 HomoloGene: 53111 GeneCards: INTS1 | |||||
| Orthologs | ||||||
| Species | Human | Mouse | ||||
| Entrez | ||||||
| Ensembl | ||||||
| UniProt | ||||||
| RefSeq (mRNA) | ||||||
| RefSeq (protein) | ||||||
| Location (UCSC) | Chr 7: 1.47 – 1.5 Mb | Chr 5: 139.75 – 139.78 Mb | ||||
| PubMed search | [1] | [2] | ||||
| Wikidata | ||||||
| View/Edit Human | View/Edit Mouse |
Integrator complex subunit 1 is a protein that in humans is encoded by the INTS1 gene. [3]
Function
INTS1 is a subunit of the Integrator complex, which associates with the C-terminal domain of RNA polymerase II large subunit (POLR2A; MIM 180660) and mediates 3-prime end processing of small nuclear RNAs U1 (RNU1; MIM 180680) and U2 (RNU2; MIM 180690) (Baillat et al., 2005 [PubMed 16239144]).
References
- ↑ "Human PubMed Reference:".
- ↑ "Mouse PubMed Reference:".
- ↑ "Entrez Gene: Integrator complex subunit 1". Retrieved 2016-06-11.
Further reading
This article incorporates text from the United States National Library of Medicine, which is in the public domain.
This article is issued from Wikipedia - version of the 7/5/2016. The text is available under the Creative Commons Attribution/Share Alike but additional terms may apply for the media files.